PDB entry 3th4

View 3th4 on RCSB PDB site
Description: Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+
Class: hydrolase/hydrolase inhibitor
Keywords: Hydrolase, Serine Protease, Blood Clotting, Soluble Tissue Factor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-08-18, released 2012-08-22
The last revision prior to the SCOPe 2.02 freeze date was dated 2012-08-22, with a file datestamp of 2012-08-17.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.206
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'H':
  Compound: Coagulation factor VII heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P08709 (0-253)
  Domains in SCOPe 2.02: d3th4h_
• Chain 'L':
  Compound: Coagulation factor VII light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P08709 (0-141)
• Chain 'T':
  Compound: tissue factor
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P13726 (0-204)
• Heterogens: BGC, FUC, MG, CA, 0GE, NA, CL, HOH

PDB Chain Sequences:

• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3th4H (H:)
  ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
  lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
  lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
  sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
  seprpgvllrapfp
  

  
  
• Chain 'L':
  No sequence available.
  
  
• Chain 'T':
  No sequence available.