PDB entry 3tgz

View 3tgz on RCSB PDB site
Description: Crystal Structure Analysis of W35F/H207W Mutant of Human CLIC1
Class: transport protein
Keywords: Glutathione Transferase, thioredoxin, ion channel, TRANSPORT PROTEIN
Deposited on 2011-08-18, released 2011-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-09-14, with a file datestamp of 2011-09-09.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.244
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: chloride intracellular channel protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIC1, G6, NCC27
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00299 (Start-240)
      • engineered mutation (34)
      • engineered mutation (206)
    Domains in SCOPe 2.08: d3tgza1, d3tgza2
  • Chain 'B':
    Compound: chloride intracellular channel protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIC1, G6, NCC27
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00299 (Start-240)
      • engineered mutation (34)
      • engineered mutation (206)
    Domains in SCOPe 2.08: d3tgzb1, d3tgzb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tgzA (A:)
maeeqpqvelfvkagsdgakigncpfsqrlfmvlflkgvtfnvttvdtkrrtetvqklcp
ggqlpfllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayikn
snpalndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnl
lpklhivqvvckkyrgftipeafrgvwrylsnayareefastcpddeeielayeqvakal
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3tgzA (A:)
pqvelfvkagsdgakigncpfsqrlfmvlflkgvtfnvttvdtkrrtetvqklcpggqlp
fllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayiknsnpal
ndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnllpklh
ivqvvckkyrgftipeafrgvwrylsnayareefastcpddeeielayeqvakalk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3tgzB (B:)
maeeqpqvelfvkagsdgakigncpfsqrlfmvlflkgvtfnvttvdtkrrtetvqklcp
ggqlpfllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayikn
snpalndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnl
lpklhivqvvckkyrgftipeafrgvwrylsnayareefastcpddeeielayeqvakal
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3tgzB (B:)
pqvelfvkagsdgakigncpfsqrlfmvlflkgvtfnvttvdtkrrtetvqklcpggqlp
fllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayiknsnpal
ndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnllpklh
ivqvvckkyrgftipeafrgvwrylsnayareefastcpddeeielayeqvakalk