PDB entry 3tfs
View 3tfs on RCSB PDB site
Description: Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer
Class: transferase/DNA
Keywords: stereoselectivity, DNA Polymerase, TRANSFERASE-DNA complex
Deposited on
2011-08-16, released
2012-03-21
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-03-21, with a file datestamp of
2012-03-16.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.193
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: DNA polymerase beta
Species: Homo sapiens [TaxId:9606]
Gene: POLB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3tfsa1, d3tfsa2, d3tfsa3 - Chain 'D':
Compound: DNA (5'-d(p*gp*tp*cp*gp*g)-3')
- Chain 'P':
Compound: DNA (5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*c)-3')
- Chain 'T':
Compound: DNA (5'-d(*cp*cp*gp*ap*cp*tp*gp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3')
- Heterogens: FHA, MG, NA, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3tfsA (A:)
mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
lgvtgvageplpvdsekdifdyiqwkyrepkdrse
Sequence, based on observed residues (ATOM records): (download)
>3tfsA (A:)
tlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtki
aekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrkne
dklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessg
dmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndeke
yphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvage
plpvdsekdifdyiqwkyrepkdrse
- Chain 'D':
No sequence available.
- Chain 'P':
No sequence available.
- Chain 'T':
No sequence available.