PDB entry 3tfs

View 3tfs on RCSB PDB site
Description: Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer
Class: transferase/DNA
Keywords: stereoselectivity, DNA Polymerase, TRANSFERASE-DNA complex
Deposited on 2011-08-16, released 2012-03-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-03-21, with a file datestamp of 2012-03-16.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.193
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3tfsa1, d3tfsa2, d3tfsa3
  • Chain 'D':
    Compound: DNA (5'-d(p*gp*tp*cp*gp*g)-3')
  • Chain 'P':
    Compound: DNA (5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*c)-3')
  • Chain 'T':
    Compound: DNA (5'-d(*cp*cp*gp*ap*cp*tp*gp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3')
  • Heterogens: FHA, MG, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3tfsA (A:)
    mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
    klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
    tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
    frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
    lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
    lgvtgvageplpvdsekdifdyiqwkyrepkdrse
    

    Sequence, based on observed residues (ATOM records): (download)
    >3tfsA (A:)
    tlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtki
    aekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrkne
    dklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessg
    dmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndeke
    yphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvage
    plpvdsekdifdyiqwkyrepkdrse
    

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.