PDB entry 3tf2

View 3tf2 on RCSB PDB site
Description: Crystal structure of the cap free human translation initiation factor eIF4E
Class: translation
Keywords: eIF4E, Translation, mRNA export, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2011-08-15, released 2011-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: eukaryotic translation initiation factor 4e
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF4E, EIF4EL1, EIF4F
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3tf2a_
  • Chain 'B':
    Compound: eukaryotic translation initiation factor 4e
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF4E, EIF4EL1, EIF4F
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3tf2b_
  • Chain 'C':
    Compound: eukaryotic translation initiation factor 4e
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF4E, EIF4EL1, EIF4F
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3tf2c_
  • Chain 'D':
    Compound: eukaryotic translation initiation factor 4e
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF4E, EIF4EL1, EIF4F
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3tf2d_
  • Heterogens: UNX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tf2A (A:)
matvepettptpnpptteeektesnqevanpehyikhplqnrwalwffkndksktwqanl
rliskfdtvedfwalynhiqlssnlmpgcdyslfkdgiepmwedeknkrggrwlitlnkq
qrrsdldrfwletllcligesfddysddvcgavvnvrakgdkiaiwttecenreavthig
rvykerlglppkivigyqshadtatksgsttknrfvv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tf2A (A:)
ikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdyslf
kdgiepmwedeknkrggrwlitlnkqqrrsdldrfwletllcligesfddysddvcgavv
nvrakgdkiaiwttecenreavthigrvykerlglppkivigyqshadtttknrfvv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3tf2B (B:)
matvepettptpnpptteeektesnqevanpehyikhplqnrwalwffkndksktwqanl
rliskfdtvedfwalynhiqlssnlmpgcdyslfkdgiepmwedeknkrggrwlitlnkq
qrrsdldrfwletllcligesfddysddvcgavvnvrakgdkiaiwttecenreavthig
rvykerlglppkivigyqshadtatksgsttknrfvv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tf2B (B:)
ikhplqnrwalwffknktwqanlrliskfdtvedfwalynhiqlssnlmpgcdyslfkdg
iepmwedeknkrggrwlitlnkqqrrsdldrfwletllcligesfddysddvcgavvnvr
akgdkiaiwttecenreavthigrvykerlglppkivigyqshadtatttknrfvv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3tf2C (C:)
matvepettptpnpptteeektesnqevanpehyikhplqnrwalwffkndksktwqanl
rliskfdtvedfwalynhiqlssnlmpgcdyslfkdgiepmwedeknkrggrwlitlnkq
qrrsdldrfwletllcligesfddysddvcgavvnvrakgdkiaiwttecenreavthig
rvykerlglppkivigyqshadtatksgsttknrfvv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tf2C (C:)
hyikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdys
lfkdgiepmwedeknkrggrwlitlnrsdldrfwletllcligesfddysddvcgavvnv
rakgdkiaiwttecenreavthigrvykerlglppkivigyqshadtatknrfvv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3tf2D (D:)
matvepettptpnpptteeektesnqevanpehyikhplqnrwalwffkndksktwqanl
rliskfdtvedfwalynhiqlssnlmpgcdyslfkdgiepmwedeknkrggrwlitlnkq
qrrsdldrfwletllcligesfddysddvcgavvnvrakgdkiaiwttecenreavthig
rvykerlglppkivigyqshadtatksgsttknrfvv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tf2D (D:)
ikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdyslf
kdgiepmwedeknkrggrwlitldldrfwletllcligesfddysddvcgavvnvrakgd
kiaiwttecenreavthigrvykerlglppkivigyqshadtknrfvv