PDB entry 3td8

View 3td8 on RCSB PDB site
Description: Structural Analysis of Pneumocystis carinii Dihydrofolate Reductase Complex with NADPH and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine
Class: oxidoreductase
Keywords: Dihydrofolate reductase, OXIDOREDUCTASE
Deposited on 2011-08-10, released 2012-04-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-11-20, with a file datestamp of 2013-11-15.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.2
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Pneumocystis carinii [TaxId:4754]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3td8a_
  • Heterogens: NDP, D2R, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3td8A (A:)
mnqqksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrk
twesiplqfrplkgrinvvitrnesldlgngihsaksldhalellyrtygsessvqinri
fviggaqlykaamdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdlesw
vgtkvphgkinedgfdyefemwtrdl

    Sequence, based on observed residues (ATOM records): (download) 
    >3td8A (A:)
ksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrktwes
iplqfrplkgrinvvitrnihsaksldhalellyrtygsessvqinrifviggaqlykaa
mdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdleswvgtkvphgkine
dgfdyefemwtrdl