PDB entry 3t88

View 3t88 on RCSB PDB site
Description: Crystal structure of Escherichia coli MenB in complex with substrate analogue, OSB-NCoA
Class: lyase/lyase inhibitor
Keywords: crotonase superfamily, LYASE-LYASE INHIBITOR complex
Deposited on 2011-08-01, released 2011-08-24
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.157
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
    Species: Escherichia coli [TaxId:562]
    Gene: b2262
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3t88a_
  • Chain 'B':
    Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
    Species: Escherichia coli [TaxId:562]
    Gene: b2262
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3t88b_
  • Chain 'C':
    Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
    Species: Escherichia coli [TaxId:562]
    Gene: b2262
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3t88c_
  • Chain 'D':
    Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
    Species: Escherichia coli [TaxId:562]
    Gene: b2262
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3t88d_
  • Chain 'E':
    Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
    Species: Escherichia coli [TaxId:562]
    Gene: b2262
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3t88e_
  • Chain 'F':
    Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
    Species: Escherichia coli [TaxId:562]
    Gene: b2262
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3t88f_
  • Heterogens: S0N, CL, PGE, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3t88A (A:)
gshmmiypdeamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkem
iqaladaryddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqir
tcpkpvvamvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivg
qkkareiwflcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaal
nadcdgqaglqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3t88A (A:)
deamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkemiqaladar
yddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqirtcpkpvva
mvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivgqkkareiw
flcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaalnadcdgqa
glqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3t88B (B:)
gshmmiypdeamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkem
iqaladaryddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqir
tcpkpvvamvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivg
qkkareiwflcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaal
nadcdgqaglqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3t88B (B:)
deamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkemiqaladar
yddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqirtcpkpvva
mvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivgqkkareiw
flcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaalnadcdgqa
glqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3t88C (C:)
gshmmiypdeamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkem
iqaladaryddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqir
tcpkpvvamvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivg
qkkareiwflcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaal
nadcdgqaglqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3t88C (C:)
deamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkemiqaladar
yddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqirtcpkpvva
mvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivgqkkareiw
flcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaalnadcdgqa
glqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3t88D (D:)
gshmmiypdeamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkem
iqaladaryddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqir
tcpkpvvamvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivg
qkkareiwflcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaal
nadcdgqaglqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3t88D (D:)
deamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkemiqaladar
yddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqirtcpkpvva
mvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivgqkkareiw
flcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaalnadcdgqa
glqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3t88E (E:)
gshmmiypdeamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkem
iqaladaryddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqir
tcpkpvvamvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivg
qkkareiwflcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaal
nadcdgqaglqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3t88E (E:)
deamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkemiqaladar
yddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqirtcpkpvva
mvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivgqkkareiw
flcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaalnadcdgqa
glqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3t88F (F:)
gshmmiypdeamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkem
iqaladaryddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqir
tcpkpvvamvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivg
qkkareiwflcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaal
nadcdgqaglqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3t88F (F:)
deamlyapvewhdcsegfediryekstdgiakitinrpqvrnafrpltvkemiqaladar
yddnigviiltgagdkafcsggdqkvrgdyggykddsgvhhlnvldfqrqirtcpkpvva
mvagysiggghvlhmmcdltiaadnaifgqtgpkvgsfdggwgasymarivgqkkareiw
flcrqydakqaldmglvntvvpladleketvrwcremlqnspmalrclkaalnadcdgqa
glqelagnatmlfymteegqegrnafnqkrqpdfskfkrnp