PDB entry 3t5i

View 3t5i on RCSB PDB site
Description: Structure of Fully modified farnesylated Rheb Peptide in complex with PDE6D
Class: lipid binding protein
Keywords: Immunoglobulin-like beta sandwitch fold, Rheb, Farnesyl, prenyl, SIGNALING PROTEIN, LIPID BINDING PROTEIN
Deposited on 2011-07-27, released 2011-11-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE6D, PDED
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3t5ia_
  • Chain 'B':
    Compound: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE6D, PDED
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3t5ib_
  • Chain 'C':
    Compound: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE6D, PDED
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3t5ic_
  • Chain 'D':
    Compound: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE6D, PDED
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3t5id_
  • Chain 'Q':
    Compound: C-terminal Farnesylated Rheb peptide CSQQGKSS(CMT)
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3T5I (Start-8)
  • Chain 'R':
    Compound: C-terminal Farnesylated Rheb peptide CSQQGKSS(CMT)
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3T5I (Start-8)
  • Heterogens: FAR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3t5iA (A:)
    gsmsakderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkcka
    vsrelnfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaapesqmm
    pasvltgnviietkffdddllvstsrvrlfyv
    

    Sequence, based on observed residues (ATOM records): (download)
    >3t5iA (A:)
    sakderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkckavsr
    elnfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaapesqmmpas
    vltgnviietkffdddllvstsrvrlfyv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3t5iB (B:)
    gsmsakderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkcka
    vsrelnfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaapesqmm
    pasvltgnviietkffdddllvstsrvrlfyv
    

    Sequence, based on observed residues (ATOM records): (download)
    >3t5iB (B:)
    kderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkckavsrel
    nfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaampasvltgnvi
    ietkffdddllvstsrvrlfyv
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3t5iC (C:)
    gsmsakderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkcka
    vsrelnfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaapesqmm
    pasvltgnviietkffdddllvstsrvrlfyv
    

    Sequence, based on observed residues (ATOM records): (download)
    >3t5iC (C:)
    sakderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkckavsr
    elnfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaapesqmmpas
    vltgnviietkffdddllvstsrvrlfyv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3t5iD (D:)
    gsmsakderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkcka
    vsrelnfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaapesqmm
    pasvltgnviietkffdddllvstsrvrlfyv
    

    Sequence, based on observed residues (ATOM records): (download)
    >3t5iD (D:)
    sakderareilrgfklnwmnlrdaetgkilwqgtedlsvpgvehearvpkkilkckavsr
    elnfssteqmekfrleqkvyfkgqcleewffefgfvipnstntwqslieaapesqmmpas
    vltgnviietkffdddllvstsrvrlfyv
    

  • Chain 'Q':
    No sequence available.

  • Chain 'R':
    No sequence available.