PDB entry 3t3x

View 3t3x on RCSB PDB site
Description: 1.57 A structure of Friedreich's ataxia frataxin variant R165C
Class: oxidoreductase
Keywords: Fe-S Cluster Biosynthesis, Human mitochondria, OXIDOREDUCTASE
Deposited on 2011-07-25, released 2011-08-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-08-31, with a file datestamp of 2011-08-26.
Experiment type: XRAY
Resolution: 1.57 Å
R-factor: 0.218
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Frataxin, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: FXN, FRDA, X25
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16595 (Start-128)
      • engineered mutation (83)
    Domains in SCOPe 2.08: d3t3xa_
  • Chain 'B':
    Compound: Frataxin, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: FXN, FRDA, X25
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16595 (Start-128)
      • engineered mutation (83)
    Domains in SCOPe 2.08: d3t3xb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3t3xA (A:)
gtlghpgsldettyerlaeetldslaeffedladkpytfedydvsfgsgvltvklggdlg
tyvinkqtpnkqiwlsspssgpkcydwtgknwvyshdgvslhellaaeltkalktkldls
slaysgkda

    Sequence, based on observed residues (ATOM records): (download) 
    >3t3xA (A:)
sldettyerlaeetldslaeffedladkpytfedydvsfgsgvltvklggdlgtyvinkq
tpnkqiwlsspssgpkcydwtgknwvyshdgvslhellaaeltkalktkldlsslaysgk
da

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3t3xB (B:)
gtlghpgsldettyerlaeetldslaeffedladkpytfedydvsfgsgvltvklggdlg
tyvinkqtpnkqiwlsspssgpkcydwtgknwvyshdgvslhellaaeltkalktkldls
slaysgkda

    Sequence, based on observed residues (ATOM records): (download) 
    >3t3xB (B:)
ldettyerlaeetldslaeffedladkpytfedydvsfgsgvltvklggdlgtyvinkqt
pnkqiwlsspssgpkcydwtgknwvyshdgvslhellaaeltkalktkldlsslaysgkd
a