PDB entry 3sxs

View 3sxs on RCSB PDB site
Description: Crystal structure of BMX non-receptor tyrosine kinase complexed with PP2
Class: transferase/transferase inhibitor
Keywords: TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-07-15, released 2011-09-21
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-11-30, with a file datestamp of 2011-11-25.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: 0.18
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytoplasmic tyrosine-protein kinase BMX
    Species: Homo sapiens [TaxId:9606]
    Gene: AGMX1, ATK, BMX, BPK, BTK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51813 (3-End)
      • expression tag (0-2)
      • engineered mutation (24)
      • engineered mutation (203)
      • engineered mutation (209)
      • engineered mutation (212)
    Domains in SCOPe 2.02: d3sxsa_
  • Heterogens: PP2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3sxsA (A:)
ghmelkreeitllkelgsgqfgvvklgkwkgqydvavkmikegsmsedeffqeaqtmmkl
shpklvkfygvcskeypiyivteyisngcllnylrshgkglepsqllemcydvcegmafl
eshqfihrdlaarnclvdrdlcvkvsdfgmtryvlddqyvssvgtkfpvkwsapevfhyf
kyssksdvwafgilmwevfslgkmpydlytnsevvlkvsqghrlyrphlasdtiyqimys
cwhelpekrptfqqllssieplrekdkh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sxsA (A:)
ghmelkreeitllkelgsgqfgvvklgkwkgqydvavkmikegsmsedeffqeaqtmmkl
shpklvkfygvcskeypiyivteyisngcllnylrshgkglepsqllemcydvcegmafl
eshqfihrdlaarnclvdrdlcvkvsdfgmtryvlddqyvssvgtkfpvkwsapevfhyf
kyssksdvwafgilmwevfslgkmpydlytnsevvlkvsqghrlyrphlasdtiyqimys
cwhelpekrptfqqllssieplre