PDB entry 3si0
View 3si0 on RCSB PDB site
Description: Structure of glycosylated human glutaminyl cyclase
Class: transferase
Keywords: alpha/beta hydrolase, Alzheimer's disease, pyroglutamate, pGlu, pE, pGlu-amyloid, glycosylation, glycoprotein, TRANSFERASE
Deposited on
2011-06-17, released
2011-06-29
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-11-08, with a file datestamp of
2017-11-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Glutaminyl-peptide cyclotransferase
Species: Homo sapiens [TaxId:9606]
Gene: QPCT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d3si0a_ - Heterogens: NAG, ZN, IMD, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3si0A (A:)
hhhhhheeknyhqpailnssalrqiaegtsisemwqndlqpllierypgspgsyaarqhi
mqriqrlqadwvleidtflsqtpygyrsfsniistlnptakrhlvlachydskyfshwnn
rvfvgatdsavpcammlelaraldkkllslktvsdskpdlslqliffdgeeaflhwspqd
slygsrhlaakmastphppgargtsqlhgmdllvlldligapnptfpnffpnsarwferl
qaiehelhelgllkdhslegryfqnysyggviqddhipflrrgvpvlhlipspfpevwht
mddneenldestidnlnkilqvfvleylhl
Sequence, based on observed residues (ATOM records): (download)
>3si0A (A:)
eeknyhqpailnssalrqiaegtsisemwqndlqpllierypgspgsyaarqhimqriqr
lqadwvleidtflsqtpygyrsfsniistlnptakrhlvlachydskyfnnrvfvgatds
avpcammlelaraldkkllslkdlslqliffdgeeaflhwspqdslygsrhlaakmastp
hppgargtsqlhgmdllvlldligapnptfpnffpnsarwferlqaiehelhelgllkdh
slegryfqnysyggviqddhipflrrgvpvlhlipspfpevwhtmddneenldestidnl
nkilqvfvleylhl