PDB entry 3se9

View 3se9 on RCSB PDB site
Description: Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120
Class: viral protein/immune system
Keywords: hiv, gp120, antibody, vrc-pg04, neutralization, vaccine, envelope glycoprotein, viral protein-immune system complex
Deposited on 2011-06-10, released 2011-08-10
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-10-05, with a file datestamp of 2011-09-30.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.192
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'G':
    Compound: HIV-1 Clade AE strain 93TH057 gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: gp120
    Database cross-references and differences (RAF-indexed):
    • PDB 3SE9 (0-352)
  • Chain 'H':
    Compound: Heavy chain of antibody VRC-PG04
    Species: Homo sapiens [TaxId:9606]
    Gene: antibody VRC-PG04 heavy chain
    Database cross-references and differences (RAF-indexed):
    • PDB 3SE9 (0-End)
  • Chain 'L':
    Compound: Light chain of antibody VRC-PG04
    Species: Homo sapiens [TaxId:9606]
    Gene: antibody VRC-PG04 light chain
    Database cross-references and differences (RAF-indexed):
    • PDB 3SE9 (0-207)
    Domains in SCOPe 2.04: d3se9l1, d3se9l2
  • Heterogens: NAG, SO4, GOL, CL, BU3, TRS, HOH

PDB Chain Sequences:

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3se9L (L:)
    eivltqspgtlslspgetaslsctaasyghmtwyqkkpgqppkllifatskrasgipdrf
    sgsqfgkqytltitrmepedfaryycqqleffgqgtrleirrtvaapsvfifppsdeqlk
    sgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskady
    ekhkvyacevthqglsspvtksfnrgec