PDB entry 3se8

View 3se8 on RCSB PDB site
Description: Crystal structure of broadly and potently neutralizing antibody VRC03 in complex with HIV-1 gp120
Class: viral protein/immune system
Keywords: hiv, gp120, antibody, vrc03, neutralization, vaccine, envelope glycoprotein, viral protein-immune system complex
Deposited on 2011-06-10, released 2011-08-10
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-08-15, with a file datestamp of 2012-08-10.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.189
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'G':
    Compound: HIV-1 Clade AE strain 93TH057 gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: gp120
    Database cross-references and differences (RAF-indexed):
    • PDB 3SE8 (0-352)
  • Chain 'H':
    Compound: Heavy chain of antibody VRC03
    Species: Homo sapiens [TaxId:9606]
    Gene: antibody VRC03 heavy chain
    Database cross-references and differences (RAF-indexed):
    • PDB 3SE8 (0-End)
  • Chain 'L':
    Compound: Light chain of antibody VRC03
    Species: Homo sapiens [TaxId:9606]
    Gene: antibody VRC03 light chain
    Database cross-references and differences (RAF-indexed):
    • PDB 3SE8 (0-End)
    Domains in SCOPe 2.04: d3se8l1, d3se8l2
  • Heterogens: NAG, SO4, EDO, TRS, HOH

PDB Chain Sequences:

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3se8L (L:)
eivltqspgilslspgetatlfckasqggnamtwyqkrrgqvprlliydtsrrasgvpdr
fvgsgsgtdffltinkldredfavyycqqfeffglgselevhrtvaapsvfifppsdeql
ksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskad
yekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >3se8L (L:)
eivltqspgilslspgetatlfckasqggnamtwyqkrrgqvprlliydtsrrasgvpdr
fvgsgsgtdffltinkldredfavyycqqfeffglgselevhrtvaapsvfifppsdeql
ksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskad
yekhkvyacevthqglsspvtksfnrge