PDB entry 3sc6

View 3sc6 on RCSB PDB site
Description: 2.65 Angstrom resolution crystal structure of dTDP-4-dehydrorhamnose reductase (rfbD) from Bacillus anthracis str. Ames in complex with NADP
Class: oxidoreductase
Keywords: dTDP-4-dehydrorhamnose reductase, rfbD, structural genomics, infectious diseases, Bacillus anthracis str. Ames, rhamnose biosynthetic pathway, Center for Structural Genomics of Infectious Diseases, CSGID, Rossmann fold, Catalyzes formation of dTDP-4-dehydro-6-deoxy-L-mannose, NADPH and H+ from dTDP-6-deoxy-L-mannose and NADP+, OXIDOREDUCTASE
Deposited on 2011-06-07, released 2011-06-22
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-06-22, with a file datestamp of 2011-06-17.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.217
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dTDP-4-dehydrorhamnose reductase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: BAS1138, BA_1231, GBAA_1231, rfbD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3sc6a_
  • Chain 'B':
    Compound: dTDP-4-dehydrorhamnose reductase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: BAS1138, BA_1231, GBAA_1231, rfbD
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q81TN9 (3-End)
      • expression tag (0-2)
    Domains in SCOPe 2.05: d3sc6b_
  • Chain 'C':
    Compound: dTDP-4-dehydrorhamnose reductase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: BAS1138, BA_1231, GBAA_1231, rfbD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3sc6c_
  • Chain 'D':
    Compound: dTDP-4-dehydrorhamnose reductase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: BAS1138, BA_1231, GBAA_1231, rfbD
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q81TN9 (3-End)
      • expression tag (1-2)
    Domains in SCOPe 2.05: d3sc6d_
  • Chain 'E':
    Compound: dTDP-4-dehydrorhamnose reductase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: BAS1138, BA_1231, GBAA_1231, rfbD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3sc6e_
  • Chain 'F':
    Compound: dTDP-4-dehydrorhamnose reductase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: BAS1138, BA_1231, GBAA_1231, rfbD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3sc6f_
  • Heterogens: NAP, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3sc6A (A:)
snamkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphii
ihcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegyde
fhnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisv
vadqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpv
steefgaaaarpkysifqhnmlrlngflqmpsweeglerffietksh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sc6A (A:)
kerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphiiihca
aytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegydefhnp
apiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisvvadq
igsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpvstee
fgaaaarpkysifqhnmlrlngflqmpsweeglerffietk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3sc6B (B:)
snamkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphii
ihcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegyde
fhnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisv
vadqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpv
steefgaaaarpkysifqhnmlrlngflqmpsweeglerffietksh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sc6B (B:)
snamkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphii
ihcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegyde
fhnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisv
vadqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpv
staaaarpkysifqhnmlrlngflqmpsweeglerffiet

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3sc6C (C:)
snamkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphii
ihcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegyde
fhnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisv
vadqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpv
steefgaaaarpkysifqhnmlrlngflqmpsweeglerffietksh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sc6C (C:)
mkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphiiihc
aaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegydefhn
papiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisvvad
qigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpvste
efgaaaarpkysifqhnmlrlngflqmpsweeglerffiet

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3sc6D (D:)
snamkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphii
ihcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegyde
fhnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisv
vadqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpv
steefgaaaarpkysifqhnmlrlngflqmpsweeglerffietksh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sc6D (D:)
namkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphiii
hcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegydef
hnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisvv
adqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpvs
teefgaaaarpkysifqhnmlrlngflqmpsweeglerffiet

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3sc6E (E:)
snamkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphii
ihcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegyde
fhnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisv
vadqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpv
steefgaaaarpkysifqhnmlrlngflqmpsweeglerffietksh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sc6E (E:)
kerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphiiihca
aytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegydefhnp
apiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisvvadq
igsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpvstee
faarpkysifqhnmlrlngflqmpsweeglerffietk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3sc6F (F:)
snamkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphii
ihcaaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegyde
fhnpapiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisv
vadqigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpv
steefgaaaarpkysifqhnmlrlngflqmpsweeglerffietksh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sc6F (F:)
mkerviitgangqlgkqlqeelnpeeydiypfdkkllditnisqvqqvvqeirphiiihc
aaytkvdqaekerdlayvinaigarnvavasqlvgaklvyistdyvfqgdrpegydefhn
papiniygaskyageqfvkelhnkyfivrtswlygkygnnfvktmirlgkereeisvvad
qigsptyvadlnvminklihtslygtyhvsntgscswfefakkifsyanmkvnvlpvste
efgaaaarpkysifqhnmlrlngflqmpsweeglerffiet