PDB entry 3s9d

View 3s9d on RCSB PDB site
Description: binary complex between IFNa2 and IFNAR2
Class: signaling protein/receptor
Keywords: human, type I interferons, IFNa2, IFNAR2, sub-complex of the interferon signaling complex, SIGNALING PROTEIN-RECEPTOR complex
Deposited on 2011-06-01, released 2011-08-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-03-21, with a file datestamp of 2012-03-16.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.204
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interferon alpha-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IFNA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01563
      • conflict (25)
      • engineered mutation (59-60)
      • engineered mutation (63)
    Domains in SCOPe 2.07: d3s9da_
  • Chain 'B':
    Compound: Interferon alpha/beta receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: IFNAR2, IFNABR, IFNARB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3s9db1, d3s9db2
  • Chain 'C':
    Compound: Interferon alpha-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IFNA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01563
      • conflict (25)
      • engineered mutation (59-60)
      • engineered mutation (63)
    Domains in SCOPe 2.07: d3s9dc_
  • Chain 'D':
    Compound: Interferon alpha/beta receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: IFNAR2, IFNABR, IFNARB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3s9dd1, d3s9dd2
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3s9dA (A:)
    adpcdlpqthslgsrrtlmllaqmrrislfsclkdrhdfgfpqeefgnqfqkaetipvla
    amiaqifnlfstkdssaawdetlldkfytelyqqlndleacviqgvgvtetplmkedsil
    avrkyfqritlylkekkyspcawevvraeimrsfslstnlqeslrske
    

    Sequence, based on observed residues (ATOM records): (download)
    >3s9dA (A:)
    slgsrrtlmllaqmrrislfsclkdrhdfgfpqeefetipvlaamiaqifnlfstkdssa
    awdetlldkfytelyqqlndleacdsilavrkyfqritlylkekkyspcawevvraeimr
    sfslstn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3s9dB (B:)
    adpesctfkislrnfrsilswelknhsivpthytllytimskpedlkvvkncanttrsfc
    dltdewrstheayvtvlegfsgnttlfscshnfwlaidmsfeppefeivgftnhinvmvk
    fpsiveeelqfdlslvieeqsegivkkhkpeikgnmsgnftyiidklipntnycvsvyle
    hsdeqaviksplkctllpp
    

    Sequence, based on observed residues (ATOM records): (download)
    >3s9dB (B:)
    ctfkislrnfrsilswelknhsivpthytllytimskpedlkvvkncanttrsfcdltde
    wrstheayvtvlegfsttlfscshnfwlaidmsfeppefeivgftnhinvmvkfpselqf
    dlslvieeqsegivkkhkpemsgnftyiidklipntnycvsvylehqaviksplkctllp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3s9dC (C:)
    adpcdlpqthslgsrrtlmllaqmrrislfsclkdrhdfgfpqeefgnqfqkaetipvla
    amiaqifnlfstkdssaawdetlldkfytelyqqlndleacviqgvgvtetplmkedsil
    avrkyfqritlylkekkyspcawevvraeimrsfslstnlqeslrske
    

    Sequence, based on observed residues (ATOM records): (download)
    >3s9dC (C:)
    slgsrrtlmllaqmrrislfsclkdrhdfgfpqpvlaamiaqifnlfstkdssaawdetl
    ldkfytelyqqlndlealavrkyfqritlylkekkyspcawevvraeimrsfslst
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3s9dD (D:)
    adpesctfkislrnfrsilswelknhsivpthytllytimskpedlkvvkncanttrsfc
    dltdewrstheayvtvlegfsgnttlfscshnfwlaidmsfeppefeivgftnhinvmvk
    fpsiveeelqfdlslvieeqsegivkkhkpeikgnmsgnftyiidklipntnycvsvyle
    hsdeqaviksplkctllpp
    

    Sequence, based on observed residues (ATOM records): (download)
    >3s9dD (D:)
    sctfkislrnfrsilswelknhsivpthytllytimskpedlkvvkncanttrsfcdltd
    ewrstheayvtvlegfsgnttlfscshnfwlaidmsfeppefeivgftnhinvmvkfpsq
    fdlslvieeqsegivkkhkpeikmsgnftyiidklipntnycvsvylehseqaviksplk
    ctllpp