PDB entry 3s91
View 3s91 on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1
Class: unknown function
Keywords: BRD3, Bromodomain containing protein 3, ORFX, RING3 like gene, RING3L, JQ1, Structural Genomics, Structural Genomics Consortium, SGC, UNKNOWN FUNCTION
Deposited on
2011-05-31, released
2011-06-29
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-06-29, with a file datestamp of
2011-06-24.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: 0.197
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 3
Species: Homo sapiens [TaxId:9606]
Gene: BRD3, KIAA0043, RING3L
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3s91a_ - Heterogens: JQ1, IPA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3s91A (A:)
smpevsnpskpgrktnqlqymqnvvvktlwkhqfawpfyqpvdaiklnlpdyhkiiknpm
dmgtikkrlennyywsasecmqdfntmftncyiynkptddivlmaqalekiflqkvaqmp
qee
Sequence, based on observed residues (ATOM records): (download)
>3s91A (A:)
tnqlqymqnvvvktlwkhqfawpfyqpvdaiklnlpdyhkiiknpmdmgtikkrlennyy
wsasecmqdfntmftncyiynkptddivlmaqalekiflqkvaqmpq