PDB entry 3s66

View 3s66 on RCSB PDB site
Description: Structures and oxygen affinities of crystalline human hemoglobin C (beta6 Lys) in the R quaternary structures
Class: oxygen transport
Keywords: hemoglobin, allostery, OXYGEN TRANSPORT
Deposited on 2011-05-25, released 2011-08-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-08-03, with a file datestamp of 2011-07-29.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.21
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemoglobin subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: HBA1, HBA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3s66a_
  • Chain 'B':
    Compound: Hemoglobin subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: HBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68871 (0-145)
      • engineered mutation (5)
    Domains in SCOPe 2.04: d3s66b_
  • Heterogens: HEM, CMO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3s66A (A:)
    vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
    kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
    vhasldkflasvstvltskyr
    

    Sequence, based on observed residues (ATOM records): (download)
    >3s66A (A:)
    vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
    kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
    vhasldkflasvstvltsk
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3s66B (B:)
    vhltpkeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
    kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
    eftppvqaayqkvvagvanalahkyh