PDB entry 3s0n

View 3s0n on RCSB PDB site
Description: Crystal Structure of Human Chymase with Benzimidazolone Inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-05-13, released 2011-07-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chymase
    Species: Homo sapiens [TaxId:9606]
    Gene: CMA1, CYH, CYM
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23946 (0-225)
      • engineered mutation (113)
      • engineered mutation (190)
      • engineered mutation (215)
    Domains in SCOPe 2.08: d3s0na_
  • Heterogens: NAG, ZN, 0BB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3s0nA (A:)
    iiggteckphsrpymayleivtsngpskfcggflirrnfvltaahcagrsitvtlgahni
    teeedtwqklevikqfrhpkyntstlhhdimllklkekasltlavgtlpfpsqknfvppg
    rmcrvagwgrtgvlkpgsdtlqevklrlmdpqacshfrdfdhnlqlcvgnprktksafkg
    dsggpllcagaaqgivsygrsdakppavftrishyqpwinqilqan