PDB entry 3s04

View 3s04 on RCSB PDB site
Description: Crystal structure of Escherichia coli type I signal peptidase in complex with an Arylomycin Lipoglycopeptide Antibiotic
Class: hydrolase/antibiotic
Keywords: mostly-beta fold, Membrane bound, serine protease, Secreted preproteins, Cytoplasmic membrane, HYDROLASE-ANTIBIOTIC complex, signal peptidase, leader peptidase, signal peptide, leader peptide, serine-lysine dyad
Deposited on 2011-05-13, released 2011-10-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.44 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Signal peptidase I
    Species: Escherichia coli [TaxId:83333]
    Gene: b2568, JW2552, lepB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3s04a_
  • Chain 'B':
    Compound: Signal peptidase I
    Species: Escherichia coli [TaxId:83333]
    Gene: b2568, JW2552, lepB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3s04b_
  • Chain 'I':
    Compound: Glyco-Arylomycin
    Species: Streptomyces sp. [TaxId:1931]
    Database cross-references and differences (RAF-indexed):
    • PDB 3S04 (0-5)
  • Chain 'J':
    Compound: Glyco-Arylomycin
    Species: Streptomyces sp. [TaxId:1931]
    Database cross-references and differences (RAF-indexed):
    • PDB 3S04 (0-5)
  • Heterogens: 02U, RAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3s04A (A:)
mivrsfiyepfqipsgsmmptlligdfilvekfaygikdpiyqktlietghpkrgdivvf
kypedpkldyikravglpgdkvtydpvskeltiqpgcssgqacenalpvtysnvepsdfv
qtfsrrnggeatsgffevpknetkengirlserketlgdvthriltvpiaqdqvgmyyqq
pgqqlatwivppgqyfmmgdnrdnsadsrywgfvpeanlvgrataiwmsfdkqegewptg
lrlsriggih

    Sequence, based on observed residues (ATOM records): (download) 
    >3s04A (A:)
fiyepfqipsgsmmptlligdfilvekfahpkrgdivvfkypedpkldyikravglpgdk
vtydpvskeltiqpgcsacenalpvtysnvepsdfvqtftsgffevpknetkengirlse
rketlgdvthriltvpiaqdqvgmyyqqpgqqlatwivppgqyfmmgdnrdnsadsrywg
fvpeanlvgrataiwmsfdlrlsriggih

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3s04B (B:)
mivrsfiyepfqipsgsmmptlligdfilvekfaygikdpiyqktlietghpkrgdivvf
kypedpkldyikravglpgdkvtydpvskeltiqpgcssgqacenalpvtysnvepsdfv
qtfsrrnggeatsgffevpknetkengirlserketlgdvthriltvpiaqdqvgmyyqq
pgqqlatwivppgqyfmmgdnrdnsadsrywgfvpeanlvgrataiwmsfdkqegewptg
lrlsriggih

    Sequence, based on observed residues (ATOM records): (download) 
    >3s04B (B:)
fiyepfqipsgsmmptlligdfilvekfatghpkrgdivvfkypedpkldyikravglpg
dkvtydpvskeltiqpgcalpvtysnvepsdfvqtfsrrnggeatsgffevpknetkeng
irlserketlgdvthriltvpiaqdqvgmyyqqpgqqlatwivppgqyfmmgdnrdnsad
srywgfvpeanlvgrataiwmsfdkqegewptglrlsriggih

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.