PDB entry 3rzi

View 3rzi on RCSB PDB site
Description: The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan
Class: transferase
Keywords: DAH7P SYNTHASE, SHIKIMATE PATHWAY, AROMATIC BIOSYNTHESIS, EVOLUTIONARY RELATIONSHIPS, TRANSFERASE, PHE+TRP-BOUND, AUGMENTED TIM-BARREL STRUCTURE,STRUCTURAL GENOMICS, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, TIM Barrel
Deposited on 2011-05-11, released 2012-01-25
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.154
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: aroG, Rv2178c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rzia_
  • Chain 'B':
    Compound: Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: aroG, Rv2178c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rzib_
  • Heterogens: MN, PHE, TRP, PO4, SO4, GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rziA (A:)
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtec
lggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >3rziA (A:)
nwtvdipidqpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpseiv
rlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvkva
riagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlvra
ltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaeiya
shealvldyeramlrlsdgpqlfdlsahtvwigertrqidgahiafaqvianpvgvklgp
nmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviwqcdpmh
gnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvteclggaqdise
tdlagryetacdprlntqqslelaflvaemlrd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3rziB (B:)
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtec
lggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >3rziB (B:)
mnwtvdipilpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpseiv
rlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvkva
riagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlvra
ltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaeiya
shealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvianpvgv
klgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviwqc
dpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvteclggaq
disetdlagryetacdprlntqqslelaflvaemlrd