PDB entry 3rz3
View 3rz3 on RCSB PDB site
Description: Human Cdc34 E2 in complex with CC0651 inhibitor
Class: ligase/ligase inhibitor
Keywords: ubiquitin conjugating enzyme domain, E2 domain, LIGASE-LIGASE INHIBITOR complex
Deposited on
2011-05-11, released
2011-07-06
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-06, with a file datestamp of
2011-07-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.223
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin-conjugating enzyme E2 R1
Species: Homo sapiens [TaxId:9606]
Gene: CDC34, UBCH3, UBE2R1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3rz3a_ - Chain 'B':
Compound: Ubiquitin-conjugating enzyme E2 R1
Species: Homo sapiens [TaxId:9606]
Gene: CDC34, UBCH3, UBE2R1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3rz3b_ - Chain 'C':
Compound: Ubiquitin-conjugating enzyme E2 R1
Species: Homo sapiens [TaxId:9606]
Gene: CDC34, UBCH3, UBE2R1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3rz3c_ - Chain 'D':
Compound: Ubiquitin-conjugating enzyme E2 R1
Species: Homo sapiens [TaxId:9606]
Gene: CDC34, UBCH3, UBE2R1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3rz3d_ - Heterogens: U94, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3rz3A (A:)
gamgspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkar
lkfpidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvr
tillsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgv
kvp
Sequence, based on observed residues (ATOM records): (download)
>3rz3A (A:)
spssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfp
idypysppafrfltkmwhpniyetgdvcisilerwnptqnvrtillsvisllnepntfsp
anvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3rz3B (B:)
gamgspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkar
lkfpidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvr
tillsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgv
kvp
Sequence, based on observed residues (ATOM records): (download)
>3rz3B (B:)
spssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfp
idypysppafrfltkmwhpniyetgdvcisilerwnptqnvrtillsvisllnepntfsp
anvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkv
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3rz3C (C:)
gamgspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkar
lkfpidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvr
tillsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgv
kvp
Sequence, based on observed residues (ATOM records): (download)
>3rz3C (C:)
sqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfpidy
pysppafrfltkmwhpniyetgdvcirwnptqnvrtillsvisllnepntfspanvdasv
myrkwkeskgkdreytdiirkqvlgtkvdaerdgvk
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3rz3D (D:)
gamgspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkar
lkfpidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvr
tillsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgv
kvp
Sequence, based on observed residues (ATOM records): (download)
>3rz3D (D:)
lllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfpidypysp
pafrfltkmwhpniyetgdvcnvrtillsvisllnepntfspanvdasvmyrkwkeskgk
dreytdiirkqvlgtkvdaerdgvkv