PDB entry 3rpn

View 3rpn on RCSB PDB site
Description: Crystal structure of human kappa class glutathione transferase in complex with S-hexylglutathione
Class: transferase/transferase inhibitor
Keywords: kappa GST, Trx domain, GSH binding, detoxification, GTX, glutathione transferase inhibitor complex, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-04-27, released 2011-07-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.185
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase kappa 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTK1, HDCMD47P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rpna_
  • Chain 'B':
    Compound: Glutathione S-transferase kappa 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTK1, HDCMD47P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rpnb_
  • Chain 'C':
    Compound: Glutathione S-transferase kappa 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTK1, HDCMD47P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rpnc_
  • Chain 'D':
    Compound: Glutathione S-transferase kappa 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTK1, HDCMD47P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rpnd_
  • Chain 'E':
    Compound: Glutathione S-transferase kappa 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTK1, HDCMD47P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rpne_
  • Chain 'F':
    Compound: Glutathione S-transferase kappa 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTK1, HDCMD47P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rpnf_
  • Heterogens: GTX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rpnA (A:)
mgplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllp
rkglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasre
lwmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacryga
fglpitvahvdgqthmlfgsdrmellahllgekwmgpippavnarllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3rpnA (A:)
gplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllpr
kglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasrel
wmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacrygaf
glpitvahvdgqthmlfgsdrmellahllgekwmgpippa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3rpnB (B:)
mgplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllp
rkglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasre
lwmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacryga
fglpitvahvdgqthmlfgsdrmellahllgekwmgpippavnarllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3rpnB (B:)
gplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllpr
kglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasrel
wmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacrygaf
glpitvahvdgqthmlfgsdrmellahllgekwmgpippa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3rpnC (C:)
mgplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllp
rkglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasre
lwmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacryga
fglpitvahvdgqthmlfgsdrmellahllgekwmgpippavnarllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3rpnC (C:)
gplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllpr
kglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasrel
wmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacrygaf
glpitvahvdgqthmlfgsdrmellahllgekwmgpippa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3rpnD (D:)
mgplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllp
rkglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasre
lwmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacryga
fglpitvahvdgqthmlfgsdrmellahllgekwmgpippavnarllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3rpnD (D:)
gplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllpr
kglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasrel
wmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacrygaf
glpitvahvdgqthmlfgsdrmellahllgekwmgpippa

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3rpnE (E:)
mgplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllp
rkglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasre
lwmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacryga
fglpitvahvdgqthmlfgsdrmellahllgekwmgpippavnarllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3rpnE (E:)
gplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllpr
kglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasrel
wmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacrygaf
glpitvahvdgqthmlfgsdrmellahllgekwmgpippa

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3rpnF (F:)
mgplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllp
rkglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasre
lwmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacryga
fglpitvahvdgqthmlfgsdrmellahllgekwmgpippavnarllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3rpnF (F:)
gplprtvelfydvlspyswlgfeilcryqniwninlqlrpslitgimkdsgnkppgllpr
kglymandlkllrhhlqipihfpkdflsvmlekgslsamrfltavnlehpemlekasrel
wmrvwsrneditepqsilaaaekagmsaeqaqgllekiatpkvknqlketteaacrygaf
glpitvahvdgqthmlfgsdrmellahllgekwmgpippa