PDB entry 3rkq

View 3rkq on RCSB PDB site
Description: NKX2.5 Homeodomain dimer bound to ANF-242 DNA
Class: transcription/DNA
Keywords: Helix-turn-Helix, DNA binding, Nucleus, TRANSCRIPTION-DNA complex
Deposited on 2011-04-18, released 2012-05-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-05-14, with a file datestamp of 2014-05-09.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.211
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Homeobox protein Nkx-2.5
  Species: Homo sapiens [TaxId:9606]
  Gene: NKX2-5, CSX, NKX2.5, NKX2E
  Database cross-references and differences (RAF-indexed):
  • Uniprot P52952 (1-57)
    • expression tag (0)
    • engineered mutation (56)
  Domains in SCOPe 2.08: d3rkqa1, d3rkqa2
• Chain 'B':
  Compound: Homeobox protein Nkx-2.5
  Species: Homo sapiens [TaxId:9606]
  Gene: NKX2-5, CSX, NKX2.5, NKX2E
  Database cross-references and differences (RAF-indexed):
  • Uniprot P52952 (1-End)
    • expression tag (0)
    • engineered mutation (56)
  Domains in SCOPe 2.08: d3rkqb1, d3rkqb2
• Chain 'C':
  Compound: anf-242 DNA
  
• Chain 'D':
  Compound: anf-242 DNA
  
• Heterogens: MG, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3rkqA (A:)
  grrkprvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkiwfqnrryksk
  

  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >3rkqB (B:)
  grrkprvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkiwfqnrryksk
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3rkqB (B:)
  grrkprvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkiwfqnrryks
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.