PDB entry 3rii
View 3rii on RCSB PDB site
Description: Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme
Class: hydrolase
Keywords: alpha-beta-alpha fold, Thiol hydroalse, Cysteine protease, deubiquitinating enzyme, ubiquitin hydrolase, HYDROLASE
Deposited on
2011-04-13, released
2011-11-09
The last revision prior to the SCOPe 2.03 freeze date was dated
2011-12-14, with a file datestamp of
2011-12-09.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.177
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L5
Species: Homo sapiens [TaxId:9606]
Gene: AD-019, CGI-70, UCH37, UCHL5
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3riia_ - Chain 'B':
Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L5
Species: Homo sapiens [TaxId:9606]
Gene: AD-019, CGI-70, UCH37, UCHL5
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3riib_ - Heterogens: EDO, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3riiA (A:)
gplgsmtgnagewclmesdpgvftelikgfgcrgaqveeiwslepenfeklkpvhglifl
fkwqpgeepagsvvqdsrldtiffakqvinnasatqaivsvllncthqdvhlgetlsefk
efsqsfdaamkglalsnsdvirqvhnsfarqqmfefdtktsakeedafhfvsyvpvngrl
yeldglregpidlgacnqddwisavrpviekriqkysegeirfnlmaivsdrk
Sequence, based on observed residues (ATOM records): (download)
>3riiA (A:)
gewclmesdpgvftelikgfgcrgaqveeiwslepenfeklkpvhgliflfkwqpgeepa
gsvvqdsrldtiffakqvinnasatqaivsvllncthqdvhlgetlsefkefsqsfdaam
kglalsnsdvirqvhnsfarqakeedafhfvsyvpvngrlyeldglregpidlgacnqdd
wisavrpviekriqkysegeirfnlmaivsdr
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3riiB (B:)
gplgsmtgnagewclmesdpgvftelikgfgcrgaqveeiwslepenfeklkpvhglifl
fkwqpgeepagsvvqdsrldtiffakqvinnasatqaivsvllncthqdvhlgetlsefk
efsqsfdaamkglalsnsdvirqvhnsfarqqmfefdtktsakeedafhfvsyvpvngrl
yeldglregpidlgacnqddwisavrpviekriqkysegeirfnlmaivsdrk
Sequence, based on observed residues (ATOM records): (download)
>3riiB (B:)
ewclmesdpgvftelikgfgcrgaqveeiwslepenfeklkpvhgliflfkwqpgeepag
svvqdsrldtiffakqvinnasatqaivsvllncthqdvhlgetlsefkefsqsfdaamk
glalsnsdvirqvhnsfartktsakeedafhfvsyvpvngrlyeldglregpidlgacnq
ddwisavrpviekriqkysegeirfnlmaivsdr