PDB entry 3rew

View 3rew on RCSB PDB site
Description: Crystal structure of an lmp2a-derived peptide bound to human class i mhc hla-a2
Class: immune system
Keywords: MHC class I, tumour antigen targeting, immune system, hla-a2, epstein barr virus, alloreactivity, glycoprotein, immune response, MHC I, immunoglobulin domain
Deposited on 2011-04-05, released 2012-01-18
The last revision prior to the SCOPe 2.01 freeze date was dated 2012-01-18, with a file datestamp of 2012-01-13.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.209
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: HLA class I histocompatibility antigen, A-2 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-A, HLAA
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-98)
  Domains in SCOPe 2.01: d3rewb_
• Chain 'C':
  Compound: Latent membrane protein 2
  Species: Human herpesvirus 4 (strain B95-8), synthetic [TaxId:10377]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P13285 (0-8)
• Chain 'D':
  Compound: HLA class I histocompatibility antigen, A-2 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-A, HLAA
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
• Chain 'E':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-98)
  Domains in SCOPe 2.01: d3rewe_
• Chain 'F':
  Compound: Latent membrane protein 2
  Species: Human herpesvirus 4 (strain B95-8), synthetic [TaxId:10377]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P13285 (0-8)
• Heterogens: IOD, EDO, CL, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3rewB (B:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3rewE (E:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'F':
  No sequence available.