PDB entry 3rew
View 3rew on RCSB PDB site
Description: Crystal structure of an lmp2a-derived peptide bound to human class i mhc hla-a2
Class: immune system
Keywords: MHC class I, tumour antigen targeting, immune system, hla-a2, epstein barr virus, alloreactivity, glycoprotein, immune response, MHC I, immunoglobulin domain
Deposited on
2011-04-05, released
2012-01-18
The last revision prior to the SCOPe 2.01 freeze date was dated
2012-01-18, with a file datestamp of
2012-01-13.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.209
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3rewb_ - Chain 'C':
Compound: Latent membrane protein 2
Species: Human herpesvirus 4 (strain B95-8), synthetic [TaxId:10377]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Chain 'E':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3rewe_ - Chain 'F':
Compound: Latent membrane protein 2
Species: Human herpesvirus 4 (strain B95-8), synthetic [TaxId:10377]
Database cross-references and differences (RAF-indexed):
- Heterogens: IOD, EDO, CL, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3rewB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>3rewE (E:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'F':
No sequence available.