PDB entry 3rep

View 3rep on RCSB PDB site
Description: Crystal structure of the ILK/alpha-parvin core complex (MnATP)
Class: cell adhesion
Keywords: cell adhesion, ank repeat, ATP-binding, cell junction, cell membrane, integrin-binding protein, membrane, nucleotide-binding, phosphoprotein, pseudokinase, actin-binding, cytoskeleton
Deposited on 2011-04-04, released 2011-04-27
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-04-27, with a file datestamp of 2011-04-22.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.206
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Integrin-linked kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: ILK, ILK1, ILK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13418 (Start-270)
      • engineered mutation (164)
      • engineered mutation (240)
    Domains in SCOPe 2.01: d3repa_
  • Chain 'B':
    Compound: Alpha-parvin
    Species: Homo sapiens [TaxId:9606]
    Gene: PARVA, MXRA2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MN, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3repA (A:)
    mnkhsgidfkqlnfltklnenhsgelwkgrwqgndivvkvlkvrdwstrksrdfneecpr
    lrifshpnvlpvlgacqsppaphptlithwmpygslynvlhegtnfvvdqsqavkfaldm
    argmaflhtlepliprhalnsrsvmidedmtarismadvkfsfqspgrmyapawvapeal
    qkkpedtnrrsadmwsfavllwelvtrevpfadlsnmeigmkvaleglrptippgisphv
    sklmkicmnedpakrpkfdmivpilekmqdk
    

    Sequence, based on observed residues (ATOM records): (download)
    >3repA (A:)
    hsgidfkqlnfltklnenhsgelwkgrwqgndivvkvlkvrdwstrksrdfneecprlri
    fshpnvlpvlgacqsppaphptlithwmpygslynvlhegtnfvvdqsqavkfaldmarg
    maflhtlepliprhalnsrsvmidedmtarismadvkfsfqspgrmyapawvapealqkk
    pedtnrrsadmwsfavllwelvtrevpfadlsnmeigmkvaleglrptippgisphvskl
    mkicmnedpakrpkfdmivpilekmqdk
    

  • Chain 'B':
    No sequence available.