PDB entry 3rcw

View 3rcw on RCSB PDB site
Description: Crystal Structure of the bromodomain of human BRD1
Class: transcription
Keywords: Transcription, Bromodomain, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2011-03-31, released 2011-06-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-04-11, with a file datestamp of 2012-04-06.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: 0.209
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwa_
  • Chain 'B':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwb_
  • Chain 'C':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwc_
  • Chain 'D':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwd_
  • Chain 'E':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwe_
  • Chain 'F':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwf_
  • Chain 'G':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwg_
  • Chain 'H':
    Compound: Bromodomain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1, BRL, BRPF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3rcwh_
  • Heterogens: MB3, ACT, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rcwA (A:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwA (A:)
lrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgy
knlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsigleea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3rcwB (B:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwB (B:)
rltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgyk
nlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsigleeasg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3rcwC (C:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwC (C:)
tpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgyknl
hefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsigl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3rcwD (D:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwD (D:)
ltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgykn
lhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsigl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3rcwE (E:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwE (E:)
rltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgyk
nlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsigleea

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3rcwF (F:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwF (F:)
ltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgykn
lhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsigle

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3rcwG (G:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwG (G:)
ltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgykn
lhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsigl

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3rcwH (H:)
smeqvamelrltpltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmr
krleaqgyknlhefeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi
gleeasgmhlperpa

    Sequence, based on observed residues (ATOM records): (download) 
    >3rcwH (H:)
pltvllrsvldqlqdkdparifaqpvslkevpdyldhikhpmdfatmrkrleaqgyknlh
efeedfdliidncmkynardtvfyraavrlrdqggvvlrqarrevdsi