PDB entry 3r63

View 3r63 on RCSB PDB site
Description: Structure of ERK2 (SPE) mutant (S246E)
Class: transferase
Keywords: Nuclear transport, phosphorylation, kinase fold, kinase, ATP binding, TRANSFERASE
Deposited on 2011-03-21, released 2011-08-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-08-17, with a file datestamp of 2011-08-12.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.191
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Mapk1, Erk2, Mapk, Prkm1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63086 (Start-357)
      • engineered mutation (245)
    Domains in SCOPe 2.05: d3r63a_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3r63A (A:)
maaaaaagpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehq
tycqrtlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhls
ndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtg
flteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilg
ilgspeqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkri
eveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyrs

    Sequence, based on observed residues (ATOM records): (download) 
    >3r63A (A:)
aaaagpqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqrtlr
eikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyfl
yqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvat
rwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspeqe
dlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalah
pyleqyydpsdepiaeapfkflddlpkeklkelifeetarfqpgyrs