PDB entry 3r5m

View 3r5m on RCSB PDB site
Description: Crystal structure of RXRalphaLBD complexed with the agonist magnolol
Class: transcription/transcription agonist
Keywords: nuclear receptor, transcription factor, TRANSCRIPTION-TRANSCRIPTION AGONIST complex
Deposited on 2011-03-18, released 2012-02-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-08, with a file datestamp of 2012-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.252
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Retinoic acid receptor RXR-alpha
  Species: Homo sapiens [TaxId:9606]
  Gene: RXRA, NR2B1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P19793
• Chain 'B':
  Compound: nuclear receptor coactivator 2
  Species: HOMO SAPIENS, synthetic [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q15596 (0-9)
• Chain 'C':
  Compound: Retinoic acid receptor RXR-alpha
  Species: Homo sapiens [TaxId:9606]
  Gene: RXRA, NR2B1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P19793
  Domains in SCOPe 2.08: d3r5mc_
• Chain 'D':
  Compound: nuclear receptor coactivator 2
  Species: HOMO SAPIENS, synthetic [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q15596 (0-9)
• Heterogens: MLO, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  Sequence, based on SEQRES records: (download)
  

  >3r5mC (C:)
  tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
  akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
  gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
  yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3r5mC (C:)
  edmpverileaelavendpvtnicqaadkqlftlvewakriphfselplddqvillragw
  nelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkt
  elgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpal
  rsiglkclehlfffkligdtpidtflmemleap
  

  
  
• Chain 'D':
  No sequence available.