PDB entry 3r5i
View 3r5i on RCSB PDB site
Description: Crystal structure of liganded Hemoglobin complexed with a potent Antisickling agent, INN-312
Class: oxygen transport, oxygen binding
Keywords: Heme protein, Antisickling, globin fold, oxygen transport, red blood cell, oxygen binding
Deposited on
2011-03-18, released
2011-04-06
The last revision prior to the SCOPe 2.03 freeze date was dated
2011-04-06, with a file datestamp of
2011-04-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.209
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3r5ia_ - Chain 'B':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3r5ib_ - Chain 'C':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3r5ic_ - Chain 'D':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3r5id_ - Heterogens: OXY, HEM, 3R5, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3r5iA (A:)
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3r5iB (B:)
vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
eftppvqaayqkvvagvanalahkyh
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>3r5iC (C:)
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>3r5iD (D:)
vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
eftppvqaayqkvvagvanalahkyh