PDB entry 3qv8

View 3qv8 on RCSB PDB site
Description: Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with benzothiazole-2,5-disulfonic acid.
Class: transferase/transferase inhibitor
Keywords: PYRUVATE KINASE, GLYCOLYSIS, TIM Barrel, Sugar kinase, ADP/ATP binding, cytosol, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-02-25, released 2011-06-29
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-09-21, with a file datestamp of 2011-09-16.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.236
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate kinase
    Species: Leishmania mexicana [TaxId:5665]
    Gene: PKY
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3qv8a1, d3qv8a2
  • Chain 'D':
    Compound: pyruvate kinase
    Species: Leishmania mexicana [TaxId:5665]
    Gene: PKY
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3qv8d1, d3qv8d2, d3qv8d3
  • Heterogens: S62, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qv8A (A:)
msqlahnltlsifdpvanyraariictigpstqsvealkgliqsgmsvarmnfshgshey
hqttinnvrqaaaelgvniaialdtkgpeirtgqfvggdavmergatcyvttdpafadkg
tkdkfyidyqnlskvvrpgnyiyiddgililqvqshedeqtlectvtnshtisdrrgvnl
pgcdvdlpavsakdrvdlqfgveqgvdmifasfirsaeqvgdvrkalgpkgrdimiicki
enhqgvqnidsiieesdgimvargdlgveipaekvvvaqkiliskcnvagkpvicatqml
esmtynprptraevsdvanavfngadcvmlsgetakgkypnevvqymaricleaqsalne
yvffnsikklqhipmsadeavcssavnsvyetkakamvvlsntgrsarlvakyrpncpiv
cvttrlqtcrqlnitqgvesvffdadklghdegkehrvaagvefakskgyvqtgdycvvi
hadhkvkgyanqtrillve

    Sequence, based on observed residues (ATOM records): (download) 
    >3qv8A (A:)
sqlahnltlsifdpvanyraariictigpstqsvealkgliqsgmsvarmnfshgsheyh
qttinnvrqaaaelgvniaialdtkgpdvdlpavsakdrvdlqfgveqgvdmifasfirs
aeqvgdvrkalgpkgrdimiickienhqgvqnidsiieesdgimvargdlgveipaekvv
vaqkiliskcnvagkpvicatqmlesmtynprptraevsdvanavfngadcvmlsgetak
gkypnevvqymaricleaqsalneyvffnsikklqhipmsadeavcssavnsvyetkaka
mvvlsntgrsarlvakyrpncpivcvttrlqtcrqlnitqgvesvffdadklghdegkeh
rvaagvefakskgyvqtgdycvvihaanqtrillve

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qv8D (D:)
msqlahnltlsifdpvanyraariictigpstqsvealkgliqsgmsvarmnfshgshey
hqttinnvrqaaaelgvniaialdtkgpeirtgqfvggdavmergatcyvttdpafadkg
tkdkfyidyqnlskvvrpgnyiyiddgililqvqshedeqtlectvtnshtisdrrgvnl
pgcdvdlpavsakdrvdlqfgveqgvdmifasfirsaeqvgdvrkalgpkgrdimiicki
enhqgvqnidsiieesdgimvargdlgveipaekvvvaqkiliskcnvagkpvicatqml
esmtynprptraevsdvanavfngadcvmlsgetakgkypnevvqymaricleaqsalne
yvffnsikklqhipmsadeavcssavnsvyetkakamvvlsntgrsarlvakyrpncpiv
cvttrlqtcrqlnitqgvesvffdadklghdegkehrvaagvefakskgyvqtgdycvvi
hadhkvkgyanqtrillve

    Sequence, based on observed residues (ATOM records): (download) 
    >3qv8D (D:)
sqlahnltlsifdpvanyraariictigpstqsvealkgliqsgmsvarmnfshgsheyh
qttinnvrqaaaelgvniaialdtkgpeirtgqfvggdavmergatcyvttdpafadkgt
kdkfyidyqnlskvvrpgnyiyiddgililqvqshedeqtlectvtnshtisdrrgvnlp
gcdvdlpavsakdrvdlqfgveqgvdmifasfirsaeqvgdvrkalgpkgrdimiickie
nhqgvqnidsiieesdgimvargdlgveipaekvvvaqkiliskcnvagkpvicatqmle
smtynprptraevsdvanavfngadcvmlsgetakgkypnevvqymaricleaqsalney
vffnsikklqhipmsadeavcssavnsvyetkakamvvlsntgrsarlvakyrpncpivc
vttrlqtcrqlnitqgvesvffdadklghdegkehrvaagvefakskgyvqtgdycvvih
adanqtrillve