PDB entry 3qt2

View 3qt2 on RCSB PDB site
Description: Structure of a cytokine ligand-receptor complex
Class: protein binding/immune system
Keywords: cytokine type I receptor fold, fibronectin type III modules, four-helical bundle, Cytokine, Ligand-receptor complex, membrane, PROTEIN BINDING-IMMUNE SYSTEM complex
Deposited on 2011-02-22, released 2012-02-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interleukin-5 receptor subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: IL5R, IL5RA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q01344
      • engineered mutation (67)
      • engineered mutation (73)
      • engineered mutation (139)
      • engineered mutation (168)
      • engineered mutation (235)
      • see remark 999 (314)
  • Chain 'B':
    Compound: Interleukin-5 receptor subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: IL5R, IL5RA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q01344
      • engineered mutation (67)
      • engineered mutation (73)
      • engineered mutation (139)
      • engineered mutation (168)
      • engineered mutation (235)
      • see remark 999 (314-315)
  • Chain 'C':
    Compound: Interleukin-5
    Species: Homo sapiens [TaxId:9606]
    Gene: Il5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3qt2c_
  • Chain 'D':
    Compound: Interleukin-5
    Species: Homo sapiens [TaxId:9606]
    Gene: Il5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3qt2d_
  • Chain 'E':
    Compound: Interleukin-5
    Species: Homo sapiens [TaxId:9606]
    Gene: Il5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3qt2e_
  • Chain 'F':
    Compound: Interleukin-5
    Species: Homo sapiens [TaxId:9606]
    Gene: Il5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3qt2f_
  • Heterogens: BGC, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qt2C (C:)
maipteiptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesq
tvqggtverlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewiies

    Sequence, based on observed residues (ATOM records): (download) 
    >3qt2C (C:)
teiptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesqtvqg
gtverlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qt2D (D:)
maipteiptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesq
tvqggtverlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewiies

    Sequence, based on observed residues (ATOM records): (download) 
    >3qt2D (D:)
ptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesqtvqggtv
erlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewiie

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3qt2E (E:)
maipteiptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesq
tvqggtverlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewiies

    Sequence, based on observed residues (ATOM records): (download) 
    >3qt2E (E:)
eiptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesqtvqgg
tverlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewi

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3qt2F (F:)
maipteiptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesq
tvqggtverlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewiies

    Sequence, based on observed residues (ATOM records): (download) 
    >3qt2F (F:)
ptsalvketlallsthrtllianetlripvpvhknhqlcteeifqgigtlesqtvqggtv
erlfknlslikkyidgqkkkcgeerrrvnqfldylqeflgvmntewiie