PDB entry 3qri

View 3qri on RCSB PDB site
Description: The crystal structure of human abl1 kinase domain in complex with DCC-2036
Class: transferase/transferase inhibitor
Keywords: ABL1, KINASE, KINASE DOMAIN, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-02-18, released 2011-06-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-06-01, with a file datestamp of 2011-05-27.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.216
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase ABL1
    Species: Homo sapiens [TaxId:9606]
    Gene: ABL1, ABL, JTK7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00519 (6-End)
      • expression tag (1-5)
    Domains in SCOPe 2.05: d3qria_
  • Chain 'B':
    Compound: Tyrosine-protein kinase ABL1
    Species: Homo sapiens [TaxId:9606]
    Gene: ABL1, ABL, JTK7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3qrib_
  • Heterogens: NA, 919, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3qriA (A:)
    tsmdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmevee
    flkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvlly
    matqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfp
    ikwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpe
    gcpekvyelmracwqwnpsdrpsfaeihqafetmfqe
    

    Sequence, based on observed residues (ATOM records): (download)
    >3qriA (A:)
    smdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveef
    lkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllym
    atqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpi
    kwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpeg
    cpekvyelmracwqwnpsdrpsfaeihqafetmfq
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3qriB (B:)
    tsmdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmevee
    flkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvlly
    matqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfp
    ikwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpe
    gcpekvyelmracwqwnpsdrpsfaeihqafetmfqe
    

    Sequence, based on observed residues (ATOM records): (download)
    >3qriB (B:)
    ydkwemertditmkhklgggqygevyegvwkkysltvavktleveeflkeaavmkeikhp
    nlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissameylek
    knfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkf
    siksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracw
    qwnpsdrpsfaeihqafetmfq