PDB entry 3qqu

View 3qqu on RCSB PDB site
Description: Cocrystal structure of unphosphorylated igf with pyrimidine 8
Class: transferase/transferase inhibitor
Keywords: igf, kinase, inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-02-16, released 2011-04-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-04-20, with a file datestamp of 2011-04-15.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.273
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qqua_
  • Chain 'B':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qqub_
  • Chain 'C':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qquc_
  • Chain 'D':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qqud_
  • Heterogens: 01P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qquA (A:)
gsvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvla
ppslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdy
yrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfv
megglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3qquA (A:)
ewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrerieflne
asvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrppslskmiqmageia
dgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgllpvrwms
peslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkpdncpdm
lfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qquB (B:)
gsvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvla
ppslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdy
yrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfv
megglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3qquB (B:)
vpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrerief
lneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpslskmiqmage
iadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgllpvrw
mspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkpdncp
dmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qquC (C:)
gsvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvla
ppslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdy
yrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfv
megglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3qquC (C:)
pdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreriefl
neasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemvlappslskm
iqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkg
llpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglld
kpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qquD (D:)
gsvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvla
ppslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdy
yrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfv
megglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3qquD (D:)
pdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreriefl
neasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemlappslskmi
qmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgl
lpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldk
pdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen