PDB entry 3qpo

View 3qpo on RCSB PDB site
Description: Structure of PDE10-inhibitor complex
Class: hydrolase/hydrolase inhibitor
Keywords: Phosphodiesterase Inhibitors, Structure-based drug design, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-02-14, released 2011-06-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-20, with a file datestamp of 2011-07-15.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.207
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
    Species: Rattus norvegicus [TaxId:10116]
    Gene: PDE10A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3qpoa_
  • Heterogens: SO4, ZN, MG, PFR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qpoA (A:)
mhhhhhhssglvprgsamgtseewqglmhfnlparicrdielfhfdigpfenmwpgifvy
mihrscgtscfeleklcrfimsvkknyrrvpyhnwkhavtvahcmyailqnnnglftdle
rkglliaclchdldhrgfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifs
tlssseyeqvleiirkaiiatdlalyfgnrkqleemyqtgslnlhnqshrdrviglmmta
cdlcsvtklwpvtkltandiyaefwaegdemkklgiqpipmmdrdkrdevpqgqlgfyna
vaipcyttltqilpptepllkacrdnlnqwekvirgeetamwisgpatskstsekptrkv
dd

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpoA (A:)
nlparicrdielfhfdigpfenmwpgifvymihrscgtscfeleklcrfimsvkknyrrv
pyhnwkhavtvahcmyailqnnnglftdlerkglliaclchdldhrgfsnsylqkfdhpl
aalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnr
kqleemyqtgslnlhnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegde
mkklgiqpipmmdrdkrdevpqgqlgfynavaipcyttltqilpptepllkacrdnlnqw
ekvir