PDB entry 3qmt
View 3qmt on RCSB PDB site
Description: Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
Class: lyase/lyase inhibitor
Keywords: tim barrel fold, orotidine 5'-monophosphate decarboxylase, inhibitor BMP, LYASE-LYASE INHIBITOR complex
Deposited on
2011-02-05, released
2012-02-08
The last revision prior to the SCOPe 2.02 freeze date was dated
2012-02-08, with a file datestamp of
2012-02-03.
Experiment type: XRAY
Resolution: 1.32 Å
R-factor: 0.165
AEROSPACI score: 0.75
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: orotidine 5'-phosphate decarboxylase
Species: Methanothermobacter thermautotrophicus str. Delta H [TaxId:187420]
Gene: pyrF, MTH_129
Database cross-references and differences (RAF-indexed):
- Uniprot O26232
- conflict (100)
- engineered mutation (181)
- engineered mutation (205)
- Chain 'B':
Compound: orotidine 5'-phosphate decarboxylase
Species: Methanothermobacter thermautotrophicus str. Delta H [TaxId:187420]
Gene: pyrF, MTH_129
Database cross-references and differences (RAF-indexed):
- Uniprot O26232
- conflict (100)
- engineered mutation (181)
- engineered mutation (205)
Domains in SCOPe 2.02: d3qmtb_ - Heterogens: BMP, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3qmtB (B:)
mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
krfgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrev
flltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflisp
gagaqggdpgetlrfadaiivgrsifladnpaaaaagiiesikdllnp
Sequence, based on observed residues (ATOM records): (download)
>3qmtB (B:)
mdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgcrii
adfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevflltemsh
pgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispgagaqggd
pgetlrfadaiivgrsifladnpaaaaagiiesikdll