PDB entry 3qkl
View 3qkl on RCSB PDB site
Description: Spirochromane Akt Inhibitors
Class: transferase/transferase inhibitor
Keywords: Kinase Domain, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2011-02-01, released
2011-03-30
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-04-20, with a file datestamp of
2011-04-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.196
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: RAC-alpha serine/threonine-protein kinase
Species: Homo sapiens [TaxId:9606]
Gene: AKT1, PKB, RAC
Database cross-references and differences (RAF-indexed):
- Uniprot P31749 (4-End)
- engineered mutation (333)
- conflict (338)
Domains in SCOPe 2.05: d3qkla_ - Chain 'C':
Compound: GSK-3 beta peptide
- Heterogens: SMR, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3qklA (A:)
gamarvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtlten
rvlqnsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivs
aldylhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylape
vledndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksl
lsgllkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfd
eeftaqmititppdqddsmecvdserrphfpqfdysassta
Sequence, based on observed residues (ATOM records): (download)
>3qklA (A:)
rvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlq
nsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldy
lhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevled
ndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgl
lkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeeft
aqmitrphfpqfdysass
- Chain 'C':
No sequence available.