PDB entry 3qk5

View 3qk5 on RCSB PDB site
Description: Crystal structure of fatty acid amide hydrolase with small molecule inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: protein-inhibitor complex, FAAH, Fatty-acid amide hydrolase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-01-31, released 2011-04-06
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-04-20, with a file datestamp of 2011-04-15.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.186
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fatty-acid amide hydrolase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Faah, Faah1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P97612 (39-End)
      • expression tag (36-38)
    Domains in SCOPe 2.05: d3qk5a_
  • Chain 'B':
    Compound: fatty-acid amide hydrolase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Faah, Faah1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3qk5b_
  • Heterogens: QK5, EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qk5A (A:)
mggshhhhhhgmasmtggqqmgrdlyddddkdrwgseletgrqkargaatrarqkqrasl
etmdkavqrfrlqnpdldsealltlpllqlvqklqsgelspeavfftylgkawevnkgtn
cvtsyltdcetqlsqaprqgllygvpvslkecfsykghdstlglslnegmpsesdcvvvq
vlklqgavpfvhtnvpqsmlsfdcsnplfgqtmnpwksskspggssggegaligsggspl
glgtdiggsirfpsafcgicglkptgnrlsksglkgcvygqtavqlslgpmardveslal
clkallcehlftldptvpplpfreevyrssrplrvgyyetdnytmpspamrralietkqr
leaaghtlipflpnnipyalevlsagglfsdggrsflqnfkgdfvdpclgdlililrlps
wfkrllslllkplfprlaaflnsmrprsaeklwklqheiemyrqsviaqwkamnldvllt
pmlgpaldlntpgratgaisytvlyncldfpagvvpvttvtaeddaqmelykgyfgdiwd
iilkkamknsvglpvavqcvalpwqeelclrfmreveqlmtpqkqps

    Sequence, based on observed residues (ATOM records): (download) 
    >3qk5A (A:)
eletgrqkargaatrarqkqrasletmdkavqrfrlqnpdldsealltlpllqlvqklqs
gelspeavfftylgkawevnkgtncvtsyltdcetqlsqaprqgllygvpvslkecfsyk
ghdstlglslnegmpsesdcvvvqvlklqgavpfvhtnvpqsmlsfdcsnplfgqtmnpw
ksskspggssggegaligsggsplglgtdiggsirfpsafcgicglkptgnrlsksglkg
cvygqtavqlslgpmardveslalclkallcehlftldptvpplpfreevyrssrplrvg
yyetdnytmpspamrralietkqrleaaghtlipflpnnipyalevlsagglfsdggrsf
lqnfkgdfvdpclgdlililrlpswfkrllslllkplfprlaaflnsmrprsaeklwklq
heiemyrqsviaqwkamnldvlltpmlgpaldlntpgratgaisytvlyncldfpagvvp
vttvtaeddaqmelykgyfgdiwdiilkkamknsvglpvavqcvalpwqeelclrfmrev
eqlmtpqkq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qk5B (B:)
mggshhhhhhgmasmtggqqmgrdlyddddkdrwgseletgrqkargaatrarqkqrasl
etmdkavqrfrlqnpdldsealltlpllqlvqklqsgelspeavfftylgkawevnkgtn
cvtsyltdcetqlsqaprqgllygvpvslkecfsykghdstlglslnegmpsesdcvvvq
vlklqgavpfvhtnvpqsmlsfdcsnplfgqtmnpwksskspggssggegaligsggspl
glgtdiggsirfpsafcgicglkptgnrlsksglkgcvygqtavqlslgpmardveslal
clkallcehlftldptvpplpfreevyrssrplrvgyyetdnytmpspamrralietkqr
leaaghtlipflpnnipyalevlsagglfsdggrsflqnfkgdfvdpclgdlililrlps
wfkrllslllkplfprlaaflnsmrprsaeklwklqheiemyrqsviaqwkamnldvllt
pmlgpaldlntpgratgaisytvlyncldfpagvvpvttvtaeddaqmelykgyfgdiwd
iilkkamknsvglpvavqcvalpwqeelclrfmreveqlmtpqkqps

    Sequence, based on observed residues (ATOM records): (download) 
    >3qk5B (B:)
tgrqkargaatrarqkqrasletmdkavqrfrlqnpdldsealltlpllqlvqklqsgel
speavfftylgkawevnkgtncvtsyltdcetqlsqaprqgllygvpvslkecfsykghd
stlglslnegmpsesdcvvvqvlklqgavpfvhtnvpqsmlsfdcsnplfgqtmnpwkss
kspggssggegaligsggsplglgtdiggsirfpsafcgicglkptgnrlsksglkgcvy
gqtavqlslgpmardveslalclkallcehlftldptvpplpfreevyrssrplrvgyye
tdnytmpspamrralietkqrleaaghtlipflpnnipyalevlsagglfsdggrsflqn
fkgdfvdpclgdlililrlpswfkrllslllkplfprlaaflnsmrprsaeklwklqhei
emyrqsviaqwkamnldvlltpmlgpaldlntpgratgaisytvlyncldfpagvvpvtt
vtaeddaqmelykgyfgdiwdiilkkamknsvglpvavqcvalpwqeelclrfmreveql
mtpqkq