PDB entry 3qjz

View 3qjz on RCSB PDB site
Description: Crystal structure of PI3K-gamma in complex with benzothiazole 1
Class: transferase/transferase inhibitor
Keywords: p110, transferase, kinase, inhibitor, ATP-binding, p84, p101, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-01-31, released 2011-03-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.234
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: PIK3CG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qjza1, d3qjza2, d3qjza3
  • Heterogens: QJZ, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qjzA (A:)
gseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwv
tskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdip
esqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkee
wplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvf
veaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapals
skasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkl
tsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatd
plnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsal
dvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfll
krglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqvieml
qkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekck
vmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesldl
cllpygcistgdkigmieivkdattiakiqqstvgntgafkdevlnhwlkekspteekfq
aaverfvyscagycvatfvlgigdrhndnimitetgnlfhidfghilgnyksflginker
vpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpql
tskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsa

    Sequence, based on observed residues (ATOM records): (download) 
    >3qjzA (A:)
sqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskp
lpeylwkkianncifivihtsqtikvspddtpgailqsfvlrvcgrdeylvgetpiknfq
wvrhclkngeeihvvldtppdpaldevrkedcdrkfrvkirgidipvtvfveaniqhgqq
vlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycvqllyyvnlllidhrfl
lrrgeyvlhmwqifnadkltsatnpdkensmsisilldempnqlrkqleaiiatdplnpl
taedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvglt
mqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglr
nkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtl
dikslsdvssqvisqlkqklenlqnpesfrvpydpglkagalaiekckvmaskkkplwle
fkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesldlcllpygcistgd
kigmieivkdattiakiqqstgafkdevlnhwlkekspteekfqaaverfvyscagycva
tfvlgigdrhndnimitetgnlfhidfghervpfvltpdflfvmgtsgkktsphfqkfqd
icvkaylalrhhtnlliilfsmmlmtgmpskedieyirdaltvgkneedakkyfldqiev
crdkgwtvqfnwflh