PDB entry 3qic

View 3qic on RCSB PDB site
Description: The structure of human glucokinase E339K mutation
Class: transferase
Keywords: Glycolysis, Kinase, Sugar Binding, Phosphorylation, Transferase
Deposited on 2011-01-27, released 2011-06-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35557 (16-End)
      • expression tag (11-15)
      • engineered mutation (343)
    Domains in SCOPe 2.08: d3qica1, d3qica2, d3qica3
  • Heterogens: GLC, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qicA (A:)
mghhhhhhenlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasv
kmlptyvrstpegsevgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedam
tgtaemlfdyisecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasg
aegnnvvgllrdaikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacym
eemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekligg
kymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqvksdtgdrkqiynilstl
glrpsttdcdivrracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvykl
hpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3qicA (A:)
yfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstp
egsevgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyi
secisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllr
daikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelveg
degrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvl
lrlvdenllfhgeaseqlrtrgafetrfvsqvksdtgdrkqiynilstlglrpsttdcdi
vrracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhas
vrrltpsceitfieseegsgrgaalvsavackk