PDB entry 3qi5

View 3qi5 on RCSB PDB site
Description: Crystal structure of human alkyladenine DNA glycosylase in complex with 3,N4-ethenocystosine containing duplex DNA
Class: hydrolase/DNA
Keywords: alkyladenine DNA glycosylase fold, AAG, Excision, DNA repair, DNA binding, Nucleus, HYDROLASE-DNA complex
Deposited on 2011-01-26, released 2011-03-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-01-18, with a file datestamp of 2012-01-13.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.239
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-3-methyladenine glycosylase
    Species: Homo sapiens [TaxId:9606]
    Gene: MPG, AAG, ANPG, MID1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29372 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.07: d3qi5a1, d3qi5a2
  • Chain 'B':
    Compound: DNA-3-methyladenine glycosylase
    Species: Homo sapiens [TaxId:9606]
    Gene: MPG, AAG, ANPG, MID1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29372 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.07: d3qi5b1, d3qi5b2
  • Chain 'C':
    Compound: DNA (5'-d(*gp*ap*cp*ap*tp*gp*(edc)p*tp*tp*gp*cp*cp*t)-3')
  • Chain 'D':
    Compound: DNA (5'-d(*gp*gp*cp*ap*ap*gp*cp*ap*tp*gp*tp*cp*a)-3')
  • Chain 'E':
    Compound: DNA (5'-d(*gp*ap*cp*ap*tp*gp*(edc)p*tp*tp*gp*cp*cp*t)-3')
  • Chain 'F':
    Compound: DNA (5'-d(*gp*gp*cp*ap*ap*gp*cp*ap*tp*gp*tp*cp*a)-3')
  • Heterogens: MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qi5A (A:)
gphmtrlgleffdqpavplaraflgqvlvrrlpngtelrgriveteaylgpedeaahsrg
grqtprnrgmfmkpgtlyvyiiygmyfcmnissqgdgacvllraleplegletmrqlrst
lrkgtasrvlkdrelcsgpsklcqalainksfdqrdlaqdeavwlergplepsepavvaa
arvgvghagewarkplrfyvrgspwvsvvdrvaeqdtqa

    Sequence, based on observed residues (ATOM records): (download) 
    >3qi5A (A:)
gphmtrlgleffdqpavplaraflgqvlvrrlpngtelrgriveteaylgpedeaahsrg
grqtprnrgmfmkpgtlyvyiiygmyfcmnissqgdgacvllraleplegletmrqlrst
lrkvlkdrelcsgpsklcqalainksfdqrdlaqdeavwlergplepsepavvaaarvgv
ewarkplrfyvrgspwvsvvdrvaeq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qi5B (B:)
gphmtrlgleffdqpavplaraflgqvlvrrlpngtelrgriveteaylgpedeaahsrg
grqtprnrgmfmkpgtlyvyiiygmyfcmnissqgdgacvllraleplegletmrqlrst
lrkgtasrvlkdrelcsgpsklcqalainksfdqrdlaqdeavwlergplepsepavvaa
arvgvghagewarkplrfyvrgspwvsvvdrvaeqdtqa

    Sequence, based on observed residues (ATOM records): (download) 
    >3qi5B (B:)
gphmtrlgleffdqpavplaraflgqvlvrrlpngtelrgriveteaylgpedeaahsrg
grqtprnrgmfmkpgtlyvyiiygmyfcmnissqgdgacvllraleplegletmrqlrst
lrkgtrvlkdrelcsgpsklcqalainksfdqrdlaqdeavwlergplepsepavvaaar
vgvagewarkplrfyvrgspwvsvvdrvae

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.