PDB entry 3qfj

View 3qfj on RCSB PDB site
Description: The complex between TCR A6 and human Class I MHC HLA-A2 with the modified TAX (Y5F) peptide
Class: immune system
Keywords: TAX peptide, nonapeptide, MHC class I, HLA-A2, TCR A6, cross-reactivity, Y5F mutation, IMMUNE SYSTEM
Deposited on 2011-01-21, released 2012-01-11
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-01-11, with a file datestamp of 2012-01-06.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: 0.221
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3qfja1, d3qfja2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.04: d3qfjb_
  • Chain 'C':
    Compound: TAX(Y5F) peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 3QFJ (0-8)
  • Chain 'D':
    Compound: A6 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QFJ (0-199)
    Domains in SCOPe 2.04: d3qfjd1, d3qfjd2
  • Chain 'E':
    Compound: A6 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QFJ (0-244)
    Domains in SCOPe 2.04: d3qfje1, d3qfje2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qfjA (A:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrwe
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qfjB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qfjD (D:)
    keveqnsgplsvpegaiaslnctysdrgsqsffwyrqysgkspelimsiysngdkedgrf
    taqlnkasqyvsllirdsqpsdsatylcavttdswgklqfgagtqvvvtpdiqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnksd
    facanafnnsiipedtffps
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qfjE (E:)
    nagvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgev
    pngynvsrsttedfplrllsaapsqtsvyfcasrpglaggrpeqyfgpgtrltvtedlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplke
    qpalndsryalssrlrvsatfwqdprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgrad