PDB entry 3qeq
View 3qeq on RCSB PDB site
Description: The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide
Class: immune system
Keywords: MART-1 peptide, nonapeptide, MHC class I, HLA-A2, TCR DMF5, TCR DMF4, cross-reactivity, cancer, melanoma, IMMUNE SYSTEM
Deposited on
2011-01-20, released
2011-07-06
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-09-07, with a file datestamp of
2011-09-02.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: 0.218
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3qeqa1, d3qeqa2 - Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
- Uniprot P61769 (1-99)
- initiating methionine (0)
Domains in SCOPe 2.06: d3qeqb1, d3qeqb2 - Chain 'C':
Compound: MART-1(27-35) peptide
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: DMF4 alpha chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3qeqd1, d3qeqd2 - Chain 'E':
Compound: DMF4 beta chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3qeqe1, d3qeqe2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3qeqA (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwe
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3qeqB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>3qeqD (D:)
qlnqspqsmfiqegedvsmnctsssifntwlwykqdpgegpvllialykageltsngrlt
aqfgitrkdsflnisasipsdvgiyfcaggtgnqfyfgtgtsltvipniqnpdpavyqlr
dskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfac
anafnnsiipedtf
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>3qeqE (E:)
dagitqsprhkvtetgtpvtlrchqtenhrymywyrqdpghglrlihysygvkdtdkgev
sdgysvsrsktedflltlesatssqtsvyfcaisevgvgqpqhfgdgtrlsiledlnkvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqdprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
rad