PDB entry 3qdg

View 3qdg on RCSB PDB site
Description: The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide
Class: immune system
Keywords: Mart-1 peptide, decapeptide, MHC class I, HLA-A2, TCR DMF5, cross-reactivity, melanoma, cancer, IMMUNE SYSTEM
Deposited on 2011-01-18, released 2011-07-06
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-09-07, with a file datestamp of 2011-09-02.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: 0.221
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3qdga1, d3qdga2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.03: d3qdgb_
  • Chain 'C':
    Compound: Mart-1 (26-35) peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 3QDG (0-9)
  • Chain 'D':
    Compound: DMF5 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QDG (0-198)
    Domains in SCOPe 2.03: d3qdgd1, d3qdgd2
  • Chain 'E':
    Compound: DMF5 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QDG (0-241)
    Domains in SCOPe 2.03: d3qdge1, d3qdge2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qdgA (A:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrwe
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qdgB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qdgD (D:)
    keveqnsgplsvpegaiaslnctysdrgsqsffwyrqysgkspelimfiysngdkedgrf
    taqlnkasqyvsllirdsqpsdsatylcavnfgggklifgqgtelsvkpniqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
    acanafnnsiipedtffps
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qdgE (E:)
    iagitqaptsqilaagrrmtlrctqdmrhnamywyrqdlglglrlihysntagttgkgev
    pdgysvsrantddfpltlasavpsqtsvyfcasslsfgteaffgqgtrltvvedlnkvfp
    pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
    lndsryalssrlrvsatfwqdprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
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