PDB entry 3qcs

View 3qcs on RCSB PDB site
Description: Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-[2-Amino-6-(4-morpholinyl)-4-pyrimidinyl]-1H-indazol-3-amine
Class: transferase/transferase inhibitor
Keywords: AGC kinase, signal transduction, ATP & Phosphoinositide, Phosphorylation on S241, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-01-17, released 2011-03-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide-dependent protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PDPK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qcsa_
  • Heterogens: GOL, SO4, 3Q1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qcsA (A:)
gpamdgtaaeprpgagslqhaqpppqprkkrpedfkfgkilgegsfstvvlarelatsre
yaikilekrhiikenkvpyvtrerdvmsrldhpffvklyftfqddeklyfglsyakngel
lkyirkigsfdetctrfytaeivsaleylhgkgiihrdlkpenillnedmhiqitdfgta
kvlspeskqaransfvgtaqyvspellteksackssdlwalgciiyqlvaglppfragne
ylifqkiikleydfpekffpkardlvekllvldatkrlgceemegygplkahpffesvtw
enlhqqtppklt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qcsA (A:)
qprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerd
vmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsa
leylhgkgiihrdlkpenillnedmhiqitdfgtakvlssfvgtaqyvspellteksack
ssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvlda
tkrlgceemegygplkahpffesvtwenlhqqtppkl