PDB entry 3qcl

View 3qcl on RCSB PDB site
Description: Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid
Class: hydrolase/hydrolase inhibitor
Keywords: TYROSINE RECEPTOR PHOSPHATASE, TWISTED MIXED BETA-SHEETS FLANKED BY {ALPHA}-HELICES, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-01-16, released 2011-12-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-12-28, with a file datestamp of 2011-12-23.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.219
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor-type tyrosine-protein phosphatase gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPG, PTPRG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23470 (6-End)
      • engineered mutation (39)
      • engineered mutation (151)
    Domains in SCOPe 2.08: d3qcla_
  • Heterogens: NXV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qclA (A:)
gshmgsmeaipvkqfvkhigelysnnqhgfsedfeevqrstadmnitaehsnhpenkhkn
ryinilaydhsrvklrplpgkdskhsdyinanyvdgynkakayiatqgplkstfedfwrm
iweqntgiivmitnlvekgrrkcdqywptenteeygniivtlkstkihacytvrrfsirn
tkvkkgqkgnpkgrqnervviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlv
hcsagvgrtgtyividsmlqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalle
ailgketevs

    Sequence, based on observed residues (ATOM records): (download) 
    >3qclA (A:)
meaipvkqfvkhigelysnnqhgfsedfeevqrstadmnitaehsnhpenkhknryinil
aydhsrvklrplpgskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntgi
ivmitnlvekgrrkcdqywptenteeygniivtlkstkihacytvrrfsirntkvkqner
vviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsm
lqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgket