PDB entry 3qb1

View 3qb1 on RCSB PDB site
Description: Interleukin-2 mutant D10
Class: cytokine
Keywords: high affinity IL-2 cytokine, CYTOKINE
Deposited on 2011-01-12, released 2012-04-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (76)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1a_
  • Chain 'B':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (76)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1b_
  • Chain 'C':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1c_
  • Chain 'D':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1d_
  • Chain 'E':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1e_
  • Chain 'F':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (76)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1f_
  • Chain 'G':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1g_
  • Chain 'H':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-135)
      • engineered mutation (76)
      • engineered mutation (82-83)
      • engineered mutation (87-88)
      • engineered mutation (94)
    Domains in SCOPe 2.08: d3qb1h_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qb1A (A:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1A (A:)
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlahsknfhfdprdvvsninvfvlelkgfmceyadetativeflnrwitfcqsii
stlt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qb1B (B:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1B (B:)
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlahsknfhfdprdvvsninvfvlelkgfmceyadetativeflnrwitfcqsii
stlt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qb1C (C:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1C (C:)
stkktqlqlehllldlqmilnginnnpkltrmltfkfympkkatelkhlqcleeelkple
evlnlanfhfdprdvvsninvfvlelkgfmceyadetativeflnrwitfcqsiistlt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qb1D (D:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1D (D:)
stkktqlqlehllldlqmilnginntfkfympkkatelkhlqcleeelkpleevlnlafh
fdprdvvsninvfvlelkgfmceyadetativeflnrwitfcqsiistlt

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3qb1E (E:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1E (E:)
stkktqlqlehllldlqmilnginnnpkltrmltfkfympkkatelkhlqcleeelkple
evlnlanfhfdprdvvsninvfvlelkmceyadetativeflnrwitfcqsiistlt

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3qb1F (F:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1F (F:)
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlahsknfhfdprdvvsninvfvlelkgfmceyadetativeflnrwitfcqsii
stlt

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3qb1G (G:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1G (G:)
stkktqlqlehllldlqmilnginntfkfympkkatelkhlqcleeelkpleevlnlanf
hfdprdvvsninvfvlelkgfmceyadetativeflnrwitfcqsiistlt

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3qb1H (H:)
adpaptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlq
cleeelkpleevlnlahsknfhfdprdvvsninvfvlelkgsettfmceyadetativef
lnrwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qb1H (H:)
stkktqlqlehllldlqmilnginnkltrmltfkfympkkatelkhlqcleeelkpleev
lnlahnfhfdprdvvsninvfvlelkgfmceyadetativeflnrwitfcqsiistlt