SCOPe 2.08: Structural Classification of Proteins

PDB entry 3q9b

View 3q9b on RCSB PDB site
Description: Crystal Structure of APAH complexed with M344
Class: hydrolase/hydrolase inhibitor
Keywords: HDAC, polyamines, Arginase Fold, Deacetylase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-01-07, released 2011-03-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.171
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9ba_
Chain 'B':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bb_
Chain 'C':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bc_
Chain 'D':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bd_
Chain 'E':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9be_
Chain 'F':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bf_
Chain 'G':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bg_
Chain 'H':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bh_
Chain 'I':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bi_
Chain 'J':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-End)
Domains in SCOPe 2.08: d3q9bj_
Chain 'K':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bk_
Chain 'L':
Compound: Acetylpolyamine amidohydrolase
Species: Mycoplana ramosa [TaxId:40837]
Gene: aphA, aph
Database cross-references and differences (RAF-indexed):
- Uniprot Q48935 (0-340)
Domains in SCOPe 2.08: d3q9bl_
Heterogens: DMS, B3N, K, NA, ZN, HOH

PDB Chain Sequences:

Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bA (A:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bB (B:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bC (C:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bD (D:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bE (E:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bF (F:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'G':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bG (G:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bH (H:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'I':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bI (I:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'J':
Sequence, based on SEQRES records: (download)

>3q9bJ (J:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Sequence, based on observed residues (ATOM records): (download)

>3q9bJ (J:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgva

Chain 'K':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bK (K:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag

Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)

>3q9bL (L:)
mrvifsedhklrnaktelyggelvppfeapfraewilaavkeagfddvvaparhgletvl
kvhdagylnfletawdrwkaagykgeaiatsfpvrrtspriptdiegqigyycnaaetai
spgtweaalssmasaidgadliaaghkaafslcrppghhagidmfggycfinnaavaaqr
lldkgakkiaildvdfhhgngtqdifyergdvffaslhgdpaeafphflgyaeetgkgag
agttanypmgrgtpysvwgealtdslkriaafgaeaivvslgvdtfeqdpisffkltspd
yitmgrtiaasgvpllvvmeggygvpeiglnvanvlkgvag