PDB entry 3q7f

View 3q7f on RCSB PDB site
Description: Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1
Class: transferase/transferase inhibitor
Keywords: protein prenyltransferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-01-04, released 2011-08-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Farnesyltransferase alpha subunit
    Species: Cryptococcus neoformans [TaxId:235443]
    Database cross-references and differences (RAF-indexed):
    • PDB 3Q7F
    Domains in SCOPe 2.08: d3q7fa_
  • Chain 'B':
    Compound: Farnesyltransferase beta subunit
    Species: Cryptococcus neoformans [TaxId:235443]
    Database cross-references and differences (RAF-indexed):
    • PDB 3Q7F
  • Heterogens: ZN, 3CX, FPP, SO4, ED2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3q7fA (A:)
mgsshhhhhhsqdlmvtstyipmsqrrswadvkpimqddgpnpvvpimyseeykdamdyf
raiaakeekseralelteiivrmnpahytvwqyrfslltslnksledelrlmnefavqnl
ksyqvwhhrlllldrispqdpvseieyihgsllpdpknyhtwaylhwlyshfstlgrise
aqwgseldwcnemlrvdgrnnsawgwrwylrvsrpgaetssrslqdeliyilksihliph
nvsawnylrgflkhfslplvpilpailpytasklnpdietveafgfpmpsdplpedtplp
vplaleyladsfieqnrvddaakvfeklsseydqmragywefrrrecae

    Sequence, based on observed residues (ATOM records): (download) 
    >3q7fA (A:)
tyipmsqrrswadvkpimqddgpnpvvpimyseeykdamdyfraiaakeekseralelte
iivrmnpahytvwqyrfslltslnksledelrlmnefavqnlksyqvwhhrlllldrisp
qdpvseieyihgsllpdpknyhtwaylhwlyshfstlgriseaqwgseldwcnemlrvdg
rnnsawgwrwylrvsrpgaetssrslqdeliyilksihliphnvsawnylrgflkhfslp
lvpilpailpytafpmpspedtplpvplaleyladsfieqnrvddaakvfeklsseydqm
ragywefrrreca

  • Chain 'B':
    No sequence available.