PDB entry 3q5k

View 3q5k on RCSB PDB site
Description: Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor
Class: chaperone
Keywords: SLEEPING SICKNESS, LEISHMANIA, HEAT SHOCK PROTEIN, Structural Genomics, Structural Genomics Consortium, SGC, CHAPERONE
Deposited on 2010-12-28, released 2011-02-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein 83-1
    Species: Leishmania major [TaxId:5664]
    Gene: LMJF33.0312
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4Q4I6 (18-230)
      • expression tag (13-17)
    Domains in SCOPe 2.08: d3q5ka1, d3q5ka2
  • Heterogens: D1U, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3q5kA (A:)
mhhhhhhssgrenlyfqgmtetfafqaeinqlmsliintfysnkeiflrelisnasdacd
kiryqsltdpsvlgesprlcirvvpdkenktltvedngigmtkadlvnnlgtiarsgtka
fmealeaggdmsmigqfgvgfysaylvadrvtvtsknnsdesyvwessaggtftitstpe
sdmkrgtritlhlkedqmeyleprrlkelikkhsefigydielmvekttek

    Sequence, based on observed residues (ATOM records): (download) 
    >3q5kA (A:)
lyfqgmtetfafqaeinqlmsliintfysnkeiflrelisnasdacdkiryqsltdpsvp
rlcirvvpdkenktltvedngigmtkadlvnnlgtiarsgtkafmealeaggdmsmigqf
gvgfysaylvadrvtvtsknnsdesyvwessaggtftitstpesdmkrgtritlhlkedq
meyleprrlkelikkhsefigydielmvettek