PDB entry 3q4z

View 3q4z on RCSB PDB site
Description: Structure of unphosphorylated PAK1 kinase domain
Class: transferase
Keywords: Kinase domain, signalling pathway, TRANSFERASE
Deposited on 2010-12-26, released 2011-12-21
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-04-11, with a file datestamp of 2012-04-06.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: 0.186
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PAK 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13153 (Start-297)
      • engineered mutation (11)
      • engineered mutation (51)
      • engineered mutation (141)
      • engineered mutation (268)
      • expression tag (298)
    Domains in SCOPe 2.05: d3q4za_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase PAK 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13153
      • engineered mutation (11)
      • engineered mutation (51)
      • engineered mutation (141)
      • engineered mutation (268)
    Domains in SCOPe 2.05: d3q4zb_
  • Heterogens: MG, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3q4zA (A:)
msdeeileklriivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqp
kkeliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqia
avcreclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgt
pywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnp
eklsaifrdflnrclemdvekrgsakeliqhqflkiakplssltpliaaakeatknnhle
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3q4zA (A:)
eeileklriivsvgdpkfekigqgasgtvytamdqevairqmnlkeliineilvmrenkn
pnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavcreclqaleflhsnq
vihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpywmapevvtrkaygpk
vdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdflnrclem
dvekrgsakeliqhqflkiakplssltpliaaakeatknnhl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3q4zB (B:)
msdeeileklriivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqp
kkeliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqia
avcreclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgt
pywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnp
eklsaifrdflnrclemdvekrgsakeliqhqflkiakplssltpliaaakeatknnhle
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3q4zB (B:)
deeileklriivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnpkkelii
neilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavcrec
lqaleflhsnqvihrniksdnillgmdgsvkltdfqskrstmvgtpywmapevvtrkayg
pkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdflnrcl
emdvekrgsakeliqhqflkiakplssltpliaaakeat